Table 3: Linear regression controlling known metabolic syndrome covariates with a subset of study participants with metabolic syndrome.
|
MetS Subsample |
|
Model 1a |
|
|
Model 2b |
|
|
Model 3c |
|
|
Coefficient |
B |
SE B |
p-value |
B |
SE B |
p-value |
B |
SE B |
p-value |
|
Intercept |
3.618 |
0.485 |
< 0.0001 |
4.574 |
0.603 |
< 0.0001 |
0.334 |
0.858 |
0.700 |
|
Fasting glucose (mg/dL) |
-0.005 |
0.001 |
< 0.0001 |
-0.007 |
0.001 |
< 0.0001 |
-0.006 |
0.001 |
< 0.001 |
|
Triglycerides (mg/dL) |
0.001 |
0.000 |
0.059 |
0.001 |
0.000 |
0.001 |
0.001 |
0.001 |
0.033 |
|
HDL (mg/dL) |
-0.013 |
0.003 |
< 0.001 |
-0.004 |
0.003 |
0.194 |
-0.002 |
0.005 |
0.705 |
|
Systolic BP (mmHg) |
0.005 |
0.002 |
0.009 |
0.006 |
0.002 |
0.019 |
0.008 |
0.003 |
0.018 |
|
Diastolic BP (mmHg) |
-0.001 |
0.003 |
0.663 |
-0.005 |
0.004 |
0.174 |
-0.001 |
0.005 |
0.794 |
|
WC (cm) |
0.024 |
0.003 |
< 0.0001 |
0.011 |
0.009 |
0.194 |
0.019 |
0.009 |
0.045 |
|
R2 |
|
0.116 |
|
|
0.245 |
|
|
0.350 |
|
Models demonstrating the influence of metabolic risk factors on uric acid (UA) level in the subsample with metabolic syndrome. Beta values (B) are expressed in mg/dL of serum uric acid. a: Unadjusted model demonstrating the influence of each metabolic risk factor on UA levels; b: Model adjusted for sex, race, hs-CRP, BMI, HOMA-IR, and smoking; c: Model adjusted for the same variables as model 2 with the addition of physical activity, blood urea nitrogen, serum creatinine, alanine aminotransferase (ALT), and prescription medications that treat hyperuricemia