Table 2: Main characteristics of the five reported cases
Smith et al. [8] | Pollock et al. [9] First lumbar puncture | Pollock et al. [9] Second lumbar puncture | Saffran et al. [10] | Alsolaiman et al. [11] | Gooch et Al. [12] | |
CSF WBC count (/mm3) Protein level (g/L) Glucose level Confirmed HSV 1 encephalitis |
259 0.86 Normal + (PCR) |
normal 0.93 Normal - (Immunofixation) |
280 2.7 Normal + (necropsy) |
68 0,51 Normal - |
20 0.41 Normal NA (MRI consistent with HSV) |
70 0.42 Normal - (PCR) |
Antiviral therapy by acyclovir | Yes (delayed of about 2 days) |
Yes (delayed of 12 days) |
Yes (delayed about 3 days |
Yes (delayed about 6 days) |
Yes (delayed about 2 or 3 days) |
|
Temporary cardiac pacing | + | - | + | + | - | |
Permanent cardiac pacing | - | + | - | - | + | |
Neurologic sequelae | - memory impairment - langage skills | NA | - | - | - | |
Recurrence of sinus node dysfunction | - | NA | - | - | - | |
Death | - | + | - | - | - | |
Encephalitis diagnosis according to IEC | Confirmed | Confirmed | Probable | Probable | Unlikely |