Table1: Comparison between studied groups
Parameters |
|
Control |
CKD |
HD patients |
P |
No. of patients |
|
30 |
30 |
30 |
|
Age (years) |
|
52.2 ± 13 |
55 ± 12 |
56 ± 10 |
> 0.05 |
Sex Male: (n, %) (46, 51.1%) Female: (n, %)
(44, 48.9%) |
|
14, 15.6 % 16, 17.8% |
18, 20% 12, 13.3% |
14, 15.6 % 16, 17.8% |
> 0.05 |
Body mass index |
|
29.1 ± 6.6 |
27.1 ± 6.2 |
27.9 ± 5.9 |
> 0.05 |
Systolic blood pressure (mmHg) |
|
129 ± 8 |
136 ± 20 |
135 ± 14 |
> 0.05 |
Diastolic blood pressure (mmHg) |
|
83 ± 4.3 |
83 ± 8 |
83 ± 7 |
> 0.05 |
Heart rate ( b /min) |
|
93 ± 8 |
85 ± 8.6 |
90 ± 9 |
< 0.001 |
Serum creatinine (mg/dl) |
|
0.74 ± 0.12 |
3.9 ± 0.9 |
8.1 ± 1.9 |
< 0.001 |
Blood urea( mg/dl) |
|
27.5 ± 10 |
110 ± 44 |
155 ± 35 |
< 0.001 |
eGFR (ml/min) |
|
107 ± 8.9 |
24.8 ± 5.9 |
------ |
< 0.001 |
Serum calcium (mg/dl) |
|
9.8 ± 0.57 |
8.6 ± 0.88 |
8.6 ± 0.75 |
> 0.05 |
Serum phosphorus ( mg/dl |
|
4.5 ± 0.32 |
5.4 ± 0.95 |
6.0 ± 1.1 |
< 0.001 |
Parathyroid hormone (pg/ml) |
|
28 ± 14 |
227 ± 103 |
449 ± 259 |
< 0.001 |
Hemoglobin levels (g/dl) |
|
12.2 ± 1.1 |
10.8 ± 1 |
10.8 ± 1.3 |
< 0.001 |
Serum uric acid (mg/dl) |
|
6.5 ± 1.5 |
7.1 ± 1.6 |
6.2 ± 1.24 |
> 0.05 |
Serum albumin (g/dl0 |
|
4.2 ± 0.32 |
3.5 ± 0.63 |
3.8 ± 0.47 |
< 0.001 |
Random blood glucose (mg/dl) |
|
106 ± 17 |
116 ± 20 |
115 ± 21 |
> 0.05 |
Cholesterol (mg/dl0 |
|
200 ± 17 |
211 ± 20 |
212 ± 27 |
> 0.001 |
Triglycerides (mg/dl) |
|
144 ± 26 |
142 ± 34 |
154 ± 47 |
> 0.001 |
LDL (mg/dl) |
|
106 ± 9.6 |
109 ± 15.6 |
114 ± 16.7 |
> 0.001 |
Left ventricular end diastolic dimension (mm) |
|
4.62 ± 0.45 |
5.18 ± 0.96 |
5.16 ± 0.81 |
< 0.05 |
Left ventricular end systolic dimension (mm) |
|
3.07 ± 0.47 |
3.53 ± 0.89 |
3.83 ± 0.87 |
< 0.05 |
Ejection fraction % |
|
68.9 ± 4.6 |
65.3 ± 4.5 |
64.2 ± 7.4 |
< 0.05 |
Fractional shortening % |
|
37.8 ± 2.4 |
36 ± 2.6 |
35.5 ± 4.2 |
< 0.05 |
Left atrial dimension (mm) |
|
3.2100 |
4.1333 |
4.2633 |
< 0.001 |
cardiac output (ml/min) |
|
5908 ± 296 |
6494 ± 1026 |
7921 ± 655 |
< 0.001 |
Pulmonary artery pressure( mmHg) |
|
23 ± 3.8 |
36 ± 9 |
44 ± 10 |
< 0.001 |