Table 1: Clinical characteristics of the study participants (N = 105).

 

 

Low coronary risk

Intermediate coronary risk

High coronary risk

 

p

Gender (F:M)

62 (56:6)

25 (18:7)

18 (3:15)

< 0.0001

Age (years)

54.1 0.8

60.2 1.7

60.4 2.1

< 0.0001

SBP (mmHg)

126.8 2.1

144.3 3.7

154.4 4.9

< 0.0001

DBP (mmHg)

76.4 1.4

85.3 2.7

85.6 3.9

< 0.01

Body weight (Kg)

83.8 2.2

82.8 3.9

86.2 5.6

NS

Body height (cm)

159.2 0.9

158.5 1.6

164.6 1.9

< 0.05

BMI (Kg/m2)

33.1 0.8

32.9 1.4

31.6 1.6

NS

BMI Cut-off levels

 

Normal (18.5-24.9 kg/m2)

Overweight (25-29.9 kg/m2)

Obese (≥ 30 kg/m2)

 

 

4 (7)

18 (29)

40 (65)

 

 

3 (12)

7 (28)

15 (60)

 

 

3 (17)

5 (28)

10 (56)

 

 

NS

Waist circumference (cm)

106.6 1.4

107.7 3.3

108.6 3.1

NS

Hip circumference (cm)

116.4 1.6

116.2 4.2

112.4 2.6

NS

WHR

0.92 0.0

0.94 0.0

0.96 0.0

< 0.05

TC (mmol/L)

4.66 0.13

5.04 0.25

4.70 0.34

NS

HDL-C (mmol/L)

1.21 0.04

1.15 0.05

1.06 0.04

NS

LDL-C (mmol/L)

2.69 0.11

3.01 0.23

2.93 0.29

NS

TG (mmol/L)

1.67 0.11

1.94 0.14

1.58 0.16

NS

FBG (mmol/L)

7.2 0.3

7.9 0.5

7.3 0.6

NS

FBG Cut-off levels

 

Normal (< 6.1 mmol/L)

IGT (6.1 - < 7 mmol/L)

DM (≥ 7 mmol/L)

 

 

30 (48)

7 (11)

25 (40)

 

 

9 (36)

3 (12)

13 (52)

 

 

3 (17)

6 (33)

9 (43)

 

 

NS

Fasting insulin (μU/ml)

16.4 1.2

17.9 4.0

18.8 3.2

NS

HOMA-IR

5.64 0.7

7.05 2.1

6.02 1.1

NS

HOMA-IS

133.8 15.6

93.1 13.6

121.4 19.0

NS

QUICK-I

0.31 0.0

0.31 0.0

0.31 0.0

NS

 

Data are given as the mean SD or as the number of subjects with percentages given in parentheses, as appropriate. Categorical data are compared by χ2 test, continuous variables are compared by Kruskal Wallis test.

BMI: Body mass index, DBP: Diastolic blood pressure, FBG: fasting blood glucose, HOMA-IR: Homeostasis model assessment insulin resistance index, HOMA-IS: homeostasis model assessment of β-cell insulin secretion, NS: non-significant, SBP: Systolic blood pressure, WHR: waist- hip ratio.