Expression of the various mRNAs involved in reactive oxygen species and H2O2 generation and dismutation in aortic wall and Perivascular Adipose Tissue (PVAT) obtained from rats fed from weaning with low-fat (LFD, n = 20) or high-fat diet (HFD, n = 16).

Table 3: Expression of the various mRNAs involved in reactive oxygen species and H2O2 generation and dismutation in aortic wall and Perivascular Adipose Tissue (PVAT) obtained from rats fed from weaning with low-fat (LFD, n = 20) or high-fat diet (HFD, n = 16).

Aortic wall				PVAT
mRNA	Diet		P	Diet		P
	LFD	HFD		LFD	HFD
p22phox	100.0 ± 7.1	83.1 ± 6.7	0.1	100.0 ± 8.6	70.8 ± 5.7	0.0096
p40phox	100.0 ± 15.9	108.6 ± 16.4	0.71	100.0 ± 9.7	81.3 ± 7.5	0.14
p47phox	100.0 ± 11.1	159.0 ± 21.4	0.014	100.0 ± 8.8	91.5 ± 6.9	0.046
p67phox	100.0 ± 9.7	131.9 ± 11.6	0.041	100.0 ± 10.2	73.6 ± 9.5	0.068
NOX2	100.0 ± 9.9	92.3 ± 9.7	0.59	100.0 ± 10.6	74.2 ± 7.2	0.06
NOX4	100.0 ± 7.2	129.9 ± 11.0	0.025	100.0 ± 15.2	80.1 ± 8.4	0.29
Xanthine oxidase	100.0 ± 7.0	143.2 ± 11.9	0.0027	100.0 ± 12.2	92.1 ± 10.4	0.63
Cytochrome c oxidase subunit I	100.0 ± 7.4	98.8 ± 9.2	0.92	100.0 ± 7.6	171.9 ± 13.4	< 0.0001
Cytochrome c oxidase subunit II	100.0 ± 16.6	80.2 ± 11.8	0.34	100.0 ± 7.7	179.7 ± 20.4	0.0004
Cytochrome c oxidase subunit III	100.0 ± 7.6	98.7 ± 11.6	0.92	100.0 ± 7.1	171.5 ± 15.1	< 0.0001
SOD-1	100.0 ± 5.3	163.9 ± 12.3	< 0.0001	100.0 ± 7.5	84.6 ± 3.7	0.086
Catalase	100.0 ± 9.6	146.2 ± 10.2	0.0023	100.0 ± 8.2	96.8 ± 5.1	0.75
UCP-1				100.0 ± 18.1	208.2 ± 12.8	< 0.0001
UCP-2				100.0 ± 7.8	100.3 ± 7.4	0.98
UCP-3				100.0 ± 13.1	157.8 ± 11.8	0.0026

Results (mean ± SE) are expressed as the percentage of LFD. SOD: Superoxide Dismutase; UCP: Uncoupling Protein.