Table 1: Technical and clinical data of percutaenous mechanical circulatory support devices used for the treatment of cardiogenic shock.
|
|
iVAC® 2.0 L |
Impella® 2.5 L |
Impella® 5.0 L |
Impella® 5.5 L |
Impella® CP |
V-A ECMO |
|
Catheter Size (F) |
11 |
9 |
9 |
9 |
9 |
|
|
Cannula Size (F) |
17 |
12 |
21 |
19 |
14 |
14-19 arterial |
|
Maximum Flow (L/min) |
2.0 |
2.5 |
5.0 |
6.0 |
4.3 |
7.0 |
|
Pump Mechanism |
Pulsatile Flow - depend on HR |
Axial flow - continuous pump |
Axial flow - continuous pump |
Axial flow - continuous pump |
Axial flow - continuous pump |
Centrifugal flow- continuous pump |
|
Blood is aspirated from |
Left Ventricle |
Left Ventricle |
Left Ventricle |
Left Ventricle |
Left Ventricle |
Right Atrium |
|
Blood is ejected in |
Aorta |
Ascending Aorta |
Ascending Aorta |
Ascending Aorta |
Ascending Aorta |
Aorta |
|
Access Site |
Femoral Artery |
Femoral Artery |
Femoral Artery |
Axillary Artery |
Femoral Artery |
Femoral Vein Femoral Artery |
|
Implantation |
Percutaneous |
Percutaneous |
Surgical |
Percutaneous |
Percutaneous |
Percutaneous |
|
LV Support |
+ |
+ |
+ |
+ |
+ |
- |
|
Indications |
· High-risk PCI · AcuteMyocardial Infarction · Cardiogenic shock · Left ventricular failure with an EF < 30%, and/or CI < 2.5 L/min/m2 |
· Advnaced HF · Cardiogenic shock · Postcardiotomy cardiogenic shock · High-risk PCI |
· Cardiogenic shock · Postcardiotomy cardiogenic shock
|
· Cardiogenic shock · Postcardiotomy cardiogenic shock
|
· Advnaced HF · Cardiogenic shock · Postcardiotomy cardiogenic shock · High-risk PCI |
|
|
Maximal duration of application |
Up to 24 hours |
Up to 4 days |
Up to 14 days |
Up to 14 days |
Up to 4 days |
|
|
Cost |
+ + |
++ + |
++++ |
++++ |
++++ |
+ (+) |
F: French; LV: Left Ventricle; L: Liter; Min: Minutes; HR: Heart Rate; HF: Heart Failure; PCI: Percutaneous Coronary Intervention; EF: Ejection Fraction; CI: Cardiac Index