Table 4: Comparison between hypertensive patients with HFpEF and HFrEF.
Variables |
HFpEF n = 76 |
HFrEF n = 26 |
p value |
Mean ± SD age (years) |
61 ± 11 |
57 ± 14 |
0.113 |
Age ≥ 55 years, n (%) |
57 (75) |
14 (53.8) |
0.023 |
Women, n (%) |
49 (64.5) |
15 (58) |
0.64 |
Inpatients, n (%) |
14 (18.4) |
11 (42.3) |
0.02 |
Diabetes, n (%) |
10 (13.2) |
6 (23.1) |
0.348 |
Symptoms, n (%) |
|
|
|
Shortness of breath |
68 (89.5) |
25 (96.2) |
0.442 |
Palpitation |
48 (63.2) |
16 (61.5) |
0.912 |
Orthopnea |
51 (67.1) |
18 (69.2) |
0.987 |
PND |
17 (22.4) |
15 (57.7) |
0.001 |
Lower limb swelling |
48 (63.2) |
15 (57.7) |
0.367 |
Right upper quadrant pain |
3 (4) |
3 (11.4) |
0.334 |
Nocturnal cough |
42 (55.3) |
20 (76.9) |
0.051 |
Physical findings |
|
|
|
Mean ± SD Pulse rate (beats/min) |
79 ± 18 |
86 ± 17 |
0.063 |
Mean ± SD SBP (mmHg) |
157 ± 23 |
142 ± 28 |
0.011 |
Mean ± SD DBP (mmHg) |
92 ± 23 |
89 ± 17 |
0.258 |
Mean ± SD BMI (kg/m2) |
29 ± 6.4 |
26.2 ± 6.6 |
0.058 |
Obesity, n (%) |
33 (43.4) |
6 (23.1) |
0.001 |
Signs, n (%) |
|
|
|
Raised JVP |
6 (7.9) |
3 (11.5) |
0.690 |
Shifted Apex beat |
13 (17.1) |
12 (46.2) |
0.005 |
Gallop rhythm |
11 (14.5) |
20 (76.9) |
0.000 |
Basal crepitation |
3 (3.9) |
7 (26.9) |
0.002 |
Lower limb edema |
30 (39.5) |
13 (50) |
0.367 |
Laboratory findings |
|
|
|
Mean ± SD Hemoglobin (g/dl) |
12.4 ± 1.6 |
11.6 ± 2 |
0.001 |
Mean ± SD Creatinine (µmol/l) |
121.5 ± 87 |
130.7 ± 117 |
0.11 |
Mean ± SD BUN (mmol/l) |
12 ± 12.7 |
12.2 ± 8.8 |
0.15 |
Mean ± SD eGFR (ml/min/1.73 m2) |
68.6 ± 24 |
70.6 ± 30 |
0.204 |
Renal dysfunction, n (%) |
22 (28.9) |
10 (38.5) |
0.463 |
Echocardiographic findings |
|
|
|
Interventricular septum in diastole (cm) |
1.35 ± 0.2 |
1.1 ± 0.3 |
0.001 |
LV internal diameter in diastole (cm) |
4.6 ± 0.6 |
5.6 ± 0.8 |
0.000 |
Left atrial volume index (ml/m2) |
32.5 ± 12 |
43.4 ± 16 |
0.001 |
Proportion with LVH, n (%)s |
57 (75) |
22 (84.6) |
0.419 |
Proportion with enlarged LA n (%) |
32 (42.1) |
16 (61.5) |
0.112 |
Mean ± SD E/E' |
15.8 ± 5 |
20.9 ± 11 |
0.002 |
BMI: Body Mass Index; PND: Paroxysmal Nocturnal Dyspnea; JVP: Jugular Venous Pressure; n: Number; SD: Standard Deviation, HFpEF: Heart Failure with Preserved Ejection Fraction; HFrEF: Heart Failure with Reduced Ejection Fraction