Table 3: MRI characteristics to distinguish CFES for DAI.

Characteristic CFES DAI
Vasogenic edema on T2/FLAIR +++ ++
Cytoxic edema- restricted diffusion on DWI +++ ++
Petechial hemorrhages on SWI imaging ++++ +++
Corpus Callosum Involvement +++ +++
Numbers of Micro hemorrhages +++++ ++
Location of Micro Hemorrhages Digitate white matter and cortex, basal ganglia, and cerebellum Superficial gray-white matter junctions, deep white matter at corners of frontal horns,
midline of the splenium of corpus callosum, septum pellucidum, parahippocampal region,
posterolateral brainstem
Size of Micro Hemorrhages Very small Large/coarse lesions
Radial Diffusivity ++++ ++
Fractional Anistropy Lower (see Bodanapally et al (20) for FA and RD threshold values) Higher