Table 1: Demographic and clinical characteristics of acute stroke patients evaluated according to PON1 gene Q192R and L55M polymorphisms.
|
|
Q192R |
p |
L55M |
p |
|||||
|
Characteristics |
Total |
|
QR |
RR |
LL |
LM |
MM |
||
|
Age (year) |
67.10 ± 12.833 |
67.22 ± 13.110 |
67.61 ± 12.961 |
63.67 ± 9.480 |
0.793 |
69.23 ± 12.968 |
65.81 ± 12.286 |
65.06 ± 13.993 |
0.355 |
|
Systolic blood pressure (mmHg) |
144.11 ± 26.797 |
145.43 ± 25.633 |
138.57 ± 30.868 |
150.00 ± 27.080 |
0.538 |
135.90 ± 25.825 |
152.68 ± 24.395 |
142.00 ± 30.048 |
0.020 |
|
Diastolic blood pressure (mmHg) |
85.55 ± 13.065 |
86.53 ± 12.444 |
81.90 ± 15.368 |
87.50 ± 9.574 |
0.351 |
81.79 ± 13.352 |
89.20 ± 12.452 |
85.33 ± 11.872 |
0.040 |
|
Body temperature (℃) |
36.40 ± 0.373 |
36.42 ± 0.369 |
36.37 ± 0.396 |
36.17 ± 0.289 |
0.471 |
36.40 ± 0.357 |
36.39 ± 0.378 |
36.45 ± 0.423 |
0.896 |
|
Respirarory rate (breaths per min) |
20.65 ± 4.125 |
20.35 ± 4.228 |
21.62 ± 4.194 |
21.00 ± 1.732 |
0.620 |
20.39 ± 3.624 |
20.50 ± 3.180 |
22.50 ± 8.803 |
0.516 |
|
Gender |
|
|
|
|
|
|
|||
|
Female |
39 (36.4) |
27 (69.2) |
10 (25.6) |
2 (5.1) |
0.730 |
19 (48.7) |
14 (35.9) |
6 (15.4) |
0.413 |
|
Male |
68 (63.6) |
51 (75.0) |
13 (19.1) |
4 (5.9) |
25 (36.8) |
33 (48.5) |
10 (14.7) |
||
|
Hypertension. n (%) |
|
|
|
|
|
|
|||
|
Yes |
66 (75.9) |
51 (77.3) |
12 (18.2) |
3 (4.5) |
0.995 |
28 (42.4) |
31 (47.0) |
7 (10.6) |
0.884 |
|
No |
21 (24.1) |
16 (76.2) |
4 (19.0) |
1 (4.8) |
9 (42.9) |
9 (12.9) |
3 (14.3) |
||
|
Diabetes mellitus. n (%) |
|
|
|
|
|
|
|||
|
Yes |
32 (37.6) |
26 (81.2) |
5 (15.6) |
1 (3.1) |
0.703 |
13 (40.6) |
15 (46.9) |
4 (12.5) |
0.965 |
|
No |
53 (62.4) |
39 (73.6) |
11 (20.8) |
3 (5.7) |
23 (43.4) |
24 (15.3) |
6 (11.3) |
||
|
Chronic renal failure. n (%) |
|
|
|
|
|
|
|||
|
Yes |
3 (3.8) |
2 (66.7) |
1 (33.3) |
0 |
0.799 |
2 (66.7) |
1 (33.3) |
0 |
0.656 |
|
No |
76 (96.2) |
57 (75.0) |
15 (19.7) |
4 (5.3) |
32 (42.1) |
36 (47.4) |
8 (10.5) |
||
|
Chronic cardiac failure. n (%) |
|
|
|
|
|
|
|||
|
Yes |
15 (18.8) |
8 (53.3) |
6 (40.0) |
1 (6.7) |
0.122 |
8 (53.3) |
7 (46.7) |
0 |
0.327 |
|
No |
65 (81.3) |
51 (78.5) |
11 (16.9) |
3 (4.6) |
27 (41.5) |
30 (46.2) |
8 (12.3) |
||
|
Mental status. n (%) |
|
|
|
|
|
|
|
|
|
|
Normal |
72 (75.0) |
54 (75.0) |
14 (19.4) |
4 (5.6) |
0.553 |
29 (40.3) |
33 (45.8) |
10 (13.9) |
0.127 |
|
Confusion |
17 (17.7) |
14 (82.4) |
3 (17.6) |
0 |
8 (47.1) |
7 (41.2) |
2 (11.8) |
||
|
Stupor |
3 (3.1) |
2 (66.7) |
1 (33.3) |
0 |
0 |
1 (33.3) |
2 (66.7) |
||
|
Coma |
4 (4.2) |
2 (50.0) |
1 (25.0) |
1 (25.0) |
3 (75.0) |
0 |
1 (25.0) |
||
|
ECG results. n (%) |
|
|
|
|
|
|
|
|
|
|
Normal |
51 (51.5) |
37 (72.5) |
11 (21.6) |
3 (5.9) |
0.972 |
15 (29.4) |
27 (52.9) |
9 (17.6) |
0.137 |
|
AF |
35 (35.4) |
25 (71.4) |
7 (20.0) |
3 (8.6) |
19 (54.3) |
14 (40.0) |
2 (5.7) |
||
|
ST abnormalities |
5 (5.1) |
4 (80.0) |
1 (20.0) |
0 |
4 (80.0) |
1 (20.0) |
0 |
||
|
Other |
8 (8.1) |
6 (75.0) |
2 (25.0) |
0 |
4 (50.0) |
3 (37.5) |
1 (12.5) |
||
Data were analyzed by analysis of variance or χ2 test. Mean plus standard deviation values are presented for age, systolic blood pressure, diastolic blood pressure, body temperature and respiratory rate. AF: Atrial fibrillation; ECG: Electrocardiography; PON1, Paraoxanase-1. The results that are statistically significant are shown in boldface.