Table 4: Characteristics of the individual and total studies examined the association between acute ischemic stroke and PON1 gene Q192R polymorphism in Turkish population.

Study

Region

Q192R

Patients

Controls

p

OR (CI 95%)

 
 

Aydin et al., 2006 (24)

─░stanbul

Genotypes

         

QQ : QR : RR

14 (21.5) : 40 (61.5) : 11 (16.9)

38 (45.2) : 35 (41.7) : 11 (13.1)

0.010

-

 

QQ : QR+RR

14 (21.5) : 51 (78.5)

38 (45.2) : 46 (54.8)

0.003

0.332 (0.160-0.690)

 

QQ+QR : RR

54 (83.1) : 11 (16.9)

73 (86.9) : 11 (13.1)

0.514

0.740 (0.299-1.832)

 

Alleles

         

Q : R

68 (52.3) : 62 (47.7)

111 (66.1) : 57 (33.9)

0.016

0.563 (0.352-0.901)

 

Demirdö─čen et al., 2009 (26)

Ankara

Genotypes

         

QQ : QR : RR

77 (44.8) : 74 (43.0) : 21 (12.2)

46 (43.8) : 50 (47.6) : 9 (8.6)

0.572

-

 

QQ : QR+RR

77 (44.8) : 95 (55.2)

46 (43.8) : 59 (56.2)

0.876

1.040 (0.638-1.695)

 

QQ+QR : RR

151 (87.8) : 21 (12.2)

96 (91.4) : 9 (8.6)

0.345

0.674 (0.296-1.533)

 

Alleles

         

Q : R

228 (66.3) : 116 (33.7)

142 (67.6) : 68 (32.4)

0.745

0.941 (0.653-1.356)

 

Present study

Tokat

Genotypes

         

QQ : QR : RR

78 (72.9) : 23 (21.5) : 6 (5.6)

58 (58.6) : 36 (36.4) : 5 (5.1)

0.061

-

 

QQ : QR+RR

78 (72.9) : 29 (27.1)

58 (58.6) : 41 (41.4)

0.030

1.901 (1.060-3.411)

 

QQ+QR : RR

101 (94.4) : 6 (5.6)

94 (94.9) : 5 (5.1)

0.859

0.895 (0.264-3.032)

 

Alleles

         

Q : R

179 (83.6) : 35 (16.4)

152 (76.8) : 46 (23.2)

0.079

1.548 (0.948-2.526)

 

Total studies

 

Genotypes

         

QQ : QR : RR

169 (49.1) : 137 (39.8) : 38 (11.0)

142 (49.3) : 121 (42.0) : 25 (8.7)

0.587

-

 

QQ : QR+RR

169 (49.1) : 175 (50.9)

142 (49.3) : 146 (50.7)

0.965

0.993 (0.726-1.358)

 

QQ+QR : RR

306 (89.0) : 38 (11.0)

263 (91.3) : 25 (8.7)

0.323

0.765 (0.450-1.302)

 

Alleles

         

Q : R

475 (69.0) : 213 (31.0)

405 (70.3) : 171 (29.7)

0.624

0.942 (0.740-1.198)

 

PON1, Paraoxinase 1. The results that are statistically significant are shown in boldface.