Parameter

No.of points (criteria for scoring)

Known underlying immunosuppresion^*

0 (no) or 18 (Yes)

Temperature (°C)

0 (< 38.4), 33 (38.4-39.4), or 49 (> 39.4)

Organomegaly

0 (no), 23 (hepatomegaly or splenomegaly), or 38 (hepatomegaly or splenomegaly)

No of cytopenias

0 (1 lineage), 24 (2 lineage), or 34 (3 lineage)

Ferritin (ng/ml)

0 (< 2,000), 35 (2,000-6,000), or 50 (> 6,000)

Triglyceride (mmoles/liter)

0 (< 1.5), 44 (1.5-4), or 64 (> 4)

Fibrinogen (gm/liter)

0 (> 2.5) or 30 (≤ 2.5)

Serum glutamic oxalocetic transaminase (Iu/liter)

0 (< 30) or 19 (≥ 30)

Hemophagocytosis features on bone marrow aspirate

0 (no) or 35 (yes)