Table 1: Correlations of C4.4A, ALDH1*1
and vimentin expression levels with clinicopathological characteristics.
|
Characteristics |
C4.4A |
ALDH1 |
Vimentin |
|||
|
Positive (n = 49) |
Negative (n = 42) |
Positive (n = 14) |
Negative (n = 77) |
Positive (n = 12) |
Negative (n = 79) |
|
|
Menopausal status |
||||||
|
Premenopausal |
22 (61.1)*2 |
14 (38.9) |
6 (16.7) |
30 (83.3) |
3 (8.3) |
33 (91.7) |
|
Postmenopausal |
27 (49.1) |
28 (50.9) |
8 (14.5) |
47 (85.5) |
9 (16.4) |
46 (83.6) |
|
Histological type |
||||||
|
Invasive ductal carcinoma |
47 (55.3) |
38 (44.7) |
13 (15.3) |
72 (84.7) |
11 (12.9) |
74 (87.1) |
|
Others |
2 (33.3) |
4 (66.7) |
1 (16.7) |
5 (83.3) |
1 (16.7) |
5 (83.3) |
|
Tumor size |
||||||
|
≤ 2cm |
37 (58.7) |
26 (41.3) |
6 (9.5) |
57 (90.5)*3 |
7 (11.1) |
56 (88.9) |
|
2 cm < |
11 (40.7) |
16 (59.3) |
8 (29.6) |
19 (70.4) |
5 (18.5) |
22 (81.5) |
|
Unknown |
1 (100) |
0 (0) |
0 (0) |
1 (100) |
0 (0) |
1 (100) |
|
Lymph node metastasis |
||||||
|
Negative |
36 (52.9) |
32 (47.1) |
11 (16.2) |
57 (83.8) |
7 (10.3) |
61 (89.7) |
|
Positive |
13 (56.5) |
10 (43.5) |
3 (13.0) |
20 (87.0) |
5 (21.7) |
18 (78.3) |
|
Nuclear grade |
||||||
|
1 |
26 (63.4) |
15 (36.6) |
5 (12.2) |
36 (87.8) |
1 (2.4) |
40 (97.6)*4 |
|
2 |
10 (47.6) |
11 (52.4) |
3 (14.3) |
18 (85.7) |
2 (9.5) |
19 (90.5) |
|
3 |
13 (44.8) |
16 (55.2) |
6 (20.7) |
23 (79.3) |
9 (31.0) |
20 (69.0) |
|
Estrogen receptor |
||||||
|
Positive |
40 (59.7) |
27 (40.3) |
7 (10.4) |
60 (89.6)*5 |
3 (4.5) |
64 (95.5)*6 |
|
Negative |
9 (37.5) |
15 (62.5) |
7 (29.2) |
17 (70.8) |
9 (37.5) |
15 (62.5) |
|
Progesterone receptor |
||||||
|
Positive |
35 (58.3) |
25 (41.7) |
6 (10.0) |
54 (90.0) |
3 (5.0) |
57 (95.0)*7 |
|
Negative |
14 (45.2) |
17 (54.8) |
8 (25.8) |
23 (74.2) |
9 (29.0) |
22 (71.0) |
|
HER2 |
||||||
|
Positive |
15 (78.9) |
4 (21.1)*8 |
6 (31.6) |
13 (68.4) |
3 (15.8) |
16 (84.2) |
|
Negative |
34 (47.2) |
38 (52.8) |
8 (11.1) |
64 (88.9) |
9 (12.5) |
63 (87.5) |
|
Ki67 |
||||||
|
0-14% |
19 (63.3) |
11 (36.7) |
2 (6.7) |
28 (93.3) |
2 (6.7) |
28 (93.3) |
|
15% ≤ |
17 (41.5) |
24 (58.5) |
6 (14.0) |
35 (85.4) |
6 (14.6) |
35 (85.4) |
|
Not determined |
13 (65.0) |
7 (35.0) |
6 (30.0) |
14 (70.0) |
4 (20.0) |
16 (80.0) |
*1 aldehyde dehydrogenase 1, *2
( %), *3 p = 0.041, *4 p =
0.0016, *5 p = 0.046, *6 p =
0.0002, *7 p = 0.0025, *8 p =
0.014