Table 1: General description of studies.
Study |
Study
design, types of cancer outcome and type of exposure |
Confounders |
No.
of Subjects/population |
Source
of data |
Baumgardt-Elms [56] |
Case
control, morbidity, testicular, occupational |
Matched
by age and region |
1066 |
Clinical and pathology departments
in 5 regions in Germany, Interviews |
Berg [57] |
Case
control brain tumors, occupational |
Age,
gender (matched), socioeconomic status, urban vs. rural area, ionizing
radiation, smoking, cell phone, demographic characteristics, transmitters and
ham radio, smoking and medical histories, occupational exposure to EMF |
2241 |
Interviews, questionnaire. Four neurological clinics in
Germany, population registries |
Calle [58] Letter |
Proportional
mortality ratio, leukemia, occupational |
Adjusted
for age and year of death |
6 radio
and telegraph operators (observed) |
Wisconsin Department of Health and
Social Services |
Cantor
[46] |
Case
control, mortality, breast cancer, occupational |
Adjusted
for age and socio economic status |
108,989
white women, 16,033 black women |
National Cancer Institute, the
National Institute for Occupational Safety and Health (NIOSH) and the
National Center for Health Statistics |
Chung
–Yi [41] |
Ecological
morbidity, all site cancers, leukemia and brain tumors, environmental |
Age,
gender, ELF, calendar year of
diagnosis, urbanization level of township |
2606
including 939 leukemia and 394 brain cancer |
National health Insurance Research
Database, Taiwan National Communication Council |
Coleman
[59] Letter |
Proportional
registration ratio(PRR), leukemia, occupational |
5-year
age group, adjusted for age |
8 cases
of telegraph/radio operators |
South-East England, South Thames
Cancer Registry |
Cooper
[60] Letter |
Ecological,
morbidity, leukemia, environmental |
Stratified
by 5-year age bands, gender and socioeconomic status |
20
leukemia cases |
West Midlands Cancer Intelligence
Unit database (Birmingham, England) |
Degrave [35] |
Cohort
mortality, all types, occupational |
Age |
7349 |
Military, Belgian National Registry,
Belgian National Cancer Registry |
Davis [61] |
Cohort,
morbidity, testicular, occupational |
Testes
disease or trauma, family history of testicular cancer, occupational exposure
to pesticides and herbicides |
340
police officers |
Interviews, SEER 1981 registry
rates. Pathology slides |
Demers
[62] |
Case
control, morbidity, breast cancer, occupational |
Age,
work history, a broad range of risk factors (not detailed), education |
527 total,
12 communication and broadcasting exposure, males |
Cancer registries and National
Cancer Institute, Interviews |
Dode [31]
|
Ecological
mortality, all site cancers, environmental |
Age,
gender |
7191 |
Health
Department of the city Belo Horizonte in Brazil, Brazilian Telecommunication
Agency, Brazilian Institute of Geography and Statistics |
Dolk [63] |
Ecological,
morbidity, all types, environmental |
Age,
socioeconomic class |
408,000
males and females |
National
Statistics office UK, cancer registry, British
Broadcasting Corporation. Population
and cases were located via postcode of residence |
Dolk
[64] |
Ecological,
morbidity, leukemia, melanoma, bladder, childhood leukemia and brain,
environmental |
Age,
socioeconomic status |
3.39
million males and females |
National
Statistics office UK, cancer registry, British Broadcasting Corporation. Population
and cases were located via postcode of residence |
Eger [16] |
Case
control morbidity, all types, environmental |
Age,
gender |
1000 |
Medical records |
Elliot
[65] |
Case
control, Brain
and CNS, leukemia, non Hodgkin's and all cancers,
environmental |
Gender,
date of birth, education, deprivation measure, population density, population
mixing |
6985
children |
All the registered cases of cancer in children aged 0-4 in
Great Britain in 1999-2001. Four national mobile phone operators provided
data |
Finkelstein
[66] |
Cohort
morbidity all types, occupational |
Age,
calendar year |
12
leukemia cases, 41 melanoma cases |
Ontario
cancer registry, 83 Ontario police departments |
Goldsmith
[47] analysis of Lilienfeld 1978 |
Cohort
mortality, all site cancers, leukemia, breast, brain, occupational |
Not
stated |
|
Lilienfeld 1978 |
Goldsmith
[36] analysis of
Robinette 1980 |
Cohort
mortality all types, occupational |
Year of
birth |
40,000
Korean war Naval personnel |
Navy
and Veterans Administration records |
Goldsmith
[47] analysis of Anderson
1986 |
Ecological
morbidity, All site cancers and leukemia, environmental |
Age |
1143
cases of all site cancers in males and females 26
leukemia cases in males and females |
Honolulu
Cancer Registry, EPA radiation measurements |
Grayson
[67] |
Nested
case control, morbidity brain tumors, occupational |
Age,
race, military rank as a surrogate for socioeconomic status. Cases and
controlled were matched |
1150
males |
US Air Force personnel records |
Groves
[68] |
Cohort
mortality, all types, occupational |
Age |
40,581
total 20,021
high exposure, males |
Department
of Veterans Affairs. Job
classification from US Navy Veteran cohort, industrial hygienists |
Ha [45] |
Ecological,
morbidity, all site cancers, breast, leukemia, lymphoma, brain cancer,
environmental |
Age |
3152
-126,523 people per area |
Clinical and pathology departments
in 5 regions in Germany, Interviews |
Ha [42] |
Case
control morbidity, leukemia and brain tumors, environmental |
Matched
on age, gender and year of diagnosis. Residential
location, population density and socioeconomic
status, industrialized environmental pollution |
5966
children (up to 15 years old) |
South Korean Medical Insurance Data
system, National Cancer Registry |
Hardell [69] |
Case
control, testicular, occupational |
Selection
of the closest subjects in birth registration number (born in the same year) |
462
total 5 radar
workers |
Swedish Cancer Registry |
Hayes [70] |
Case
control, morbidity, testicular, occupational |
Age,
radioisotopes, radioactive materials or nuclear materials, pesticides,
polycyclic aromatic hydrocarbons |
530
males |
Three collaborating medical
institutions in Washington DC area, two of the study hospitals were military
hospitals |
Hocking
[71] |
Ecological,
morbidity and mortality, children and adults, leukemia and brain tumors,
environmental |
Age,
gender, calendar period, area |
585,000
males and females |
New South Wales Cancer Registry
(Australia), Commonwealth Department of Communication and Arts |
Hocking
[39] |
Survival
ecological, leukemia, environmental |
Age,
gender and year of diagnosis |
160
children |
New South Wales (Australia) cancer
registry |
Holly [72] |
Case
control, morbidity Uveal melanoma, occupational |
Demographic
characteristics, occupational history, and exposure to chemicals. Excluded
home microwave ovens |
668
males |
Ocular Oncology Unity at the
University of California San Francisco, interviews |
Karipidis [73] |
Case
control, morbidity non Hodgkin's lymphoma,
occupational |
Matched
on age, gender and area of residence. Occupational exposure, risk factors of
NHL, ionizing radiation, chemicals |
1388
males and females |
New
South Wales Central Cancer Registry, Australia. New South Wales and Austrian Capital
Territory electoral polls |
Karipidis [74] |
Case
control, Morbidity Glioma, occupational |
Age,
gender, postcode of residence. Occupational exposure, education. Job
exposure matrix included exposures to ELF, RF, UV and ionizing radiation |
838 |
14 Melbourne hospitals, Victoria
Cancer Registy,
major population centers in the state of Victoria, Australia.
Questionnaires and interviews |
Kliukiene [75] |
Nested
case control within a cohort, morbidity breast cancer, occupational |
Job
histories, Match on year of birth, exposures |
495
within a cohort of 2619 |
National cancer registry of Norway |
Lagorio [30] |
Cohort
mortality, all site cancers, leukemia, brain, Digestive, liver, lung, breast,
occupational |
Age,
gender, calendar period – specific regional mortality rates to the person
years at risk |
481 females |
Registry Office of the
municipalities |
Maskarinec [76] |
Case
control morbidity, leukemia, environmental |
Age,
gender, medical history, exposure to metals, smoking in the home, X rays,
proximity to oil drums, parents occupational history and exposure to metals,
chemicals. Case and controls were matched on gender and age |
60
cases and controls, children |
Hawaii Tumor Registry, Interviews |
Mcdowall
[27] Letter |
Proportional
mortality ratio (PMR), leukemia, occupational |
- |
6
telegraph radio operators (no. of cases) |
Office of population censuses and
surveys, England and Wales electrical occupations |
McKenzie
[77] |
Ecological,
leukemia morbidity, environmental |
Age and
socioeconomic status |
216
children |
New South Wales Central Cancer
Registry |
Merzenich [78] |
Case
control morbidity, leukemia, environmental |
Age,
gender and transmitter area (matching), population density |
7807 |
German childhood cancer registry
(1984- 2003) |
Michelozzi [79] |
Ecological,
mortality, morbidity, childhood and adult leukemia, environmental |
Age,
gender, socioeconomic class |
49,656
adults and children |
Lazio
Region Geographic information mortality system, Italian Cancer Registries,
main hospitals in Rome, Residence data: local population register, and census
tract |
Milham [29] Letter |
Proportionate
mortality ratio (PMR), leukemia, occupational |
Standardized
by age and year of death |
5 radio and telegraph operators, 5 TV and radio repairman, no. of observed |
All
deaths of Washington State. Washington State department of Social and Health
Services |
Milham [80] |
Proportionate
Mortality Ratio (PMR), leukemia, lymphoma, lung, brain, pancreas,
occupational |
Age,
year of death |
486,000
males total |
Records
of male deaths filed in Washington State |
Milham [81] Letter |
Proportionate
mortality ratio (PMR), leukemia occupational |
Age |
1691
male deaths. Of them 24 with leukemia |
Washington
State and California, radio operators monthly magazine that lists deaths on
monthly basis |
Milham [82] |
Cohort
mortality, all types, occupational |
Age |
67,829
amateur radio operators |
US
Federal Communications Commission Amateur Radio Station and/or Operator
License file from the National Technical Information Services |
Milham [26] |
Cohort,
mortality, Hematologic, lymphatic and brain cancer, occupational |
Age |
67,829
amateur radio operators |
US
Federal Communications Commission Amateur Radio Station and/or Operator
License file from the National Technical Information Services |
Morgan
[83] |
Cohort,
mortality, brain, lymphatic/hematopoietic, Hodgkin's, melanoma,
respiratory system, stomach, breast, occupational |
Age,
gender, race |
195,775
total 24,621
exposed |
National
Death Index, Social Security Administration, archived personnel files |
Pearce
[84] |
Case
control morbidity, leukemia, occupational |
Matched
on Age and year of registration |
6 radio/TV repair, males |
New
Zealand cancer registry |
Pearce
[85] |
Case
control, morbidity, leukemia, occupational |
Age |
12 radio/TV repair, males |
New
Zealand Cancer Registry |
Szmigielski [37] |
Cohort,
morbidity, all types, occupational |
Age,
diagnosis date |
128,000
total 3,700
exposed, males |
Military's
health departments, hospitals, medical board, safety groups operating as
health hygienic service |
Szmigielski [38] |
Cohort
morbidity all types, occupational |
Age |
124,500
total, about 3500-4500 exposed males |
Polish
army, service records listing of exposures |
Thomas
[86] |
Case
control, mortality, brain tumor, occupational |
Educational
level, match on age at death, year of death and area of residence. Risk
factors of brain tumor |
821death
certificates, males |
Northern
New Jersey, Philadelphia, PA, and southern Louisiana. Brain
tumors verified through a hospital record review |
Tynes [87] |
Cohort
morbidity, all types, occupational |
Sea
related lifestyle factors: A diet rich in fat, artificial light, disturbances
in the geomagnetic field, alcohol |
2619
females |
National
Cancer Registry of Norway |
Wolf [17] |
Cohort
morbidity all sites, environmental |
Socioeconomic
class employment status, demographic heterogeneity due to differences in age
gender and ethnicity |
1844 |
Medical
clinics, national and city incidence rate |
Wright [28] Letter |
Proportional
Incidence Ratio (PIR) leukemia, occupational |
Specific
for age, gender and race |
1 no.
of cases (TV and radio repair) |
Cancer
Surveillance Program information on Los
Angeles County |