Table 4: List of most common SNEA regulators
identified in five tumors from three cancer patients.
SNEA regulator |
Gene ID |
Patients Count |
Cell Process |
PDGF |
Functional Class |
5 |
EMT |
F2 |
2147 |
4 |
Thrombosis, Angiogenesis |
KLF5 |
688 |
4 |
EMT |
OSM |
5008 |
4 |
Tumor inflammation |
PLAU |
5328 |
4 |
Thrombosis, UrokinaseR signaling |
PLG |
5340 |
4 |
Thrombosis, Angiogenesis |
CDKN2A |
1029 |
3 |
Cell cycle |
CTGF |
1490 |
3 |
ECM->EMT |
E2F3 |
1871 |
3 |
Cell cycle |
ephrin-B |
Functional Class |
3 |
|
F10 |
2159 |
3 |
Thrombosis |
HB-EGF |
1839 |
3 |
EGFR activation |
IGF2 |
3481 |
3 |
EMT |
IL1A |
3552 |
3 |
|
KDR |
3791 |
3 |
Angiogenesis |
LIN9 |
286826 |
3 |
Cell cycle |
MMP3 |
4314 |
3 |
ECM->EMT |
MYBL2 |
4605 |
3 |
Cell cycle |
NOX1 |
11125 |
3 |
ROS activation |
OLR1 |
4973 |
3 |
Oxidize-LDL |
P2RY6 |
5031 |
3 |
Apoptotic clearance |
PDGFD |
80310 |
3 |
EMT |
PPAP2B |
8613 |
3 |
EGFR activation |
PRKCD |
5580 |
3 |
Apoptotic clearance |
SH2B3 |
10019 |
3 |
|
SLC39A1 |
27173 |
3 |
|
SPARC |
6678 |
3 |
ECM->EMT |
TGFB2 |
7042 |
3 |
EMT, N1->N2 neutrophil
polarization |
THBS1 |
7057 |
3 |
Apoptotic clearance |