Table 3: Univariate and Multivariable Cox regression analyses of PPS.

　

　

PPS

Variable

Reference
Group

Univariate

Multivariate

Hazard Ratio (95% CI)

p Value

Hazard Ratio (95% CI)

p Value

Age ≥`65

< 65

1.09 (0.58-2.03)

0.80

1.05 (0.53-2.09)

0.89

ER positive

ER negative

1.24 (0.64-2.38)

0.56

0.57 (0.26-1.24)

0.16

Prior lines of chemotherapy ≥ 2

< 2

1.05 (0.44-2.53)

0.91

0.46 (0.17-1.22)

0.12

Total dose of Eribulin ≥ 10 mg/m2

< 10 mg/m2

0.59 (0.30-1.17)

0.132

0.26 (0.12-0.57)

0.001

Visceral disease

Non-visceral

3.17 (1.29-7.76)

0.012

7.33 (2.49-21.6)

< 0.001

A new lesion or metastasis

IPEL

2.07 (1.08-3.96)

0.029

2.84 (1.34-6.02)

0.006

 

IPEL: in size of pre-existing lesion