Table 2: IC50 values for resminostat anti-proliferative activity against NSCLC cells.

Cell IC50 (μmol/L) KRAS status Note
A437 5.3 wild
Calu-3 2.0 wild
NCI-H522 8.7 wild
NCI-H1975 5.0 wild EGFR-TKI-resistant
NCI-H2126 3.4 wild
A549 3.3 G12S
COR-L23 4.2 G12V
MOR/CPR 0.74 G12C CDDP-resistant
NCI-H23 4.4 G12C
NCI-H358 0.36 G12C
NCI-H460 4.5 Q61H CDDP-resistant