Table 2: Factors involved in angiogenesis.
| Pro-angiogenic agents | Anti-angiogenic agents | |
|---|---|---|
| Vascular endothelial growth factor | Fibroblast growth factor | Angiopoietin II |
| Angiopoietin I | Insulin-like growth factor | Angiostatin |
| Platelet-derived growth factor | Placental growth factor | Endostatin |
| Epidermal growth factor | Tumor necrosis factor α & β | Fumagillin |
| Hepatocyte growth factor | Plateletâactivating factor | Thrombospondin 1 & 2 |
| Transforming growth factor β | ||
| Interferon α, β, γ | ||