Table 5: Relationships between immunohistochemical positivity for αβ-crystallin and laminin-332 and basal-like/penta negative profiles.
Biomarker and result | Basal-like (CK5/6 and/or EGFR positive) n = 57 | Penta negative (CK5/6 and EGFR negative) n = 12 | Total | Chi2 exact P |
αβ-Crystallin | ||||
Negative | 12 (22%) | 6 (50%) | 18 | 0.073 |
Positive | 42 (78%) | 6 (50%) | 48 | |
Total | 54 | 12 | 66 | |
Laminin-332 | ||||
Negative | 17 (30%) | 8 (67%) | 25 | 0.022 |
Positive | 40 (70%) | 4 (33%) | 44 | |
Total | 57 | 12 | 69 |