Table 1: Histopathological characteristics of the radical cystectomy specimen and the 30-day mortality rate (total group).
DUOS center | Total | ||||||
No | Yes | P-value | |||||
N | % | N | % | N | % | ||
Number of identified LNs | < 0.0001 | ||||||
Number of dissected/counted LN not documented | 198 | 22 | 412 | 16 | < 0.001 | 610 | 18 |
1-9 | 277 | 31 | 832 | 32 | 1109 | 32 | |
≥ 10 | 414 | 47 | 1339 | 52 | 1753 | 50 | |
Number of positive LNs | < 0.001 | ||||||
No positive LNs | 610 | 69 | 1899 | 74 | 2509 | 72 | |
1-4 | 146 | 16 | 460 | 18 | 606 | 17 | |
5-9 | 15 | 2 | 48 | 2 | 63 | 2 | |
≥ 10 | 9 | 1 | 16 | < 1 | 25 | 1 | |
Positive LNs documented, but number unknown | 4 | < 1 | 10 | < 1 | 14 | < 1 | |
No documentation of positive LNs | 105 | 12 | 150 | 6 | 255 | 7 | |
Surgical margins of cystectomy | 0.02 | ||||||
negative | 782 | 88 | 2301 | 89 | 3083 | 89 | |
positive | 80 | 9 | 171 | 7 | 251 | 7 | |
Unknown | 27 | 3 | 111 | 4 | 138 | 4 | |
30-day postoperative mortality | 21 | 2.4 | 56 | 2.2 | 0.90 | 77 | 2 |
Complete pathological response (ypT0N0 ) after NAC and RC | 23 | 29 | 66 | 27 | 0.70 | 89 | 28 |
Pathological stage (pT) at RC | 0.11 | ||||||
pT0 | 37 | 4 | 83 | 3 | 120 | 3% | |
pT1 | 27 | 3 | 82 | 3 | 109 | 3% | |
pT2 | 352 | 40 | 1025 | 40 | 1377 | 40% | |
pT3 | 367 | 41 | 1051 | 41 | 1418 | 41% | |
pT4 | 94 | 11 | 264 | 10 | 358 | 10% | |
pTX or pT missing | 12 | 1 | 78 | 3 | 90 | 3% |