Table 2: Risk of breast cancer in female Hodgkin's patients and their relatives, 1966-20141
Comparison | Breast Cancer HR | 95% CI | P |
Baseline BC risk in FDR of BC patients in Utah | 1.8 | (1.7-1.8) | < 0.0001 |
Risk in HL patients vs. controls | |||
BC risk in HL patients when BC in FDR | 3.8 | (1.9-7.7) | 0.0003 |
BC risk in HL patients when no BC in FDR | 1.7 | (1.2-2.5) | 0.002 |
Risk in HL patients only | |||
HL with BC in FDR vs. HL with no BC in FDR | 3.3 | (1.6-7.1) | 0.002 |
HL with BC in FDR vs. HL with no BC in FDR, for HL diagnosed 1966-1999 | 3.7 | (1.7-7.9) | < 0.001 |
Risk in FDR of HL vs. FDR of controls: | |||
FDR of HL patients with BC | 2.8 | (1.4-5.6) | 0.005 |
FDR of HL diagnosed 1966-1999 with BC | 2.9 | (1.4-5.9) | 0.003 |
FDR of HL patients with no BC | 1 | (0.8-1.4) | 0.97 |
FDR of HL diagnosed 1966-1999 with no BC | 0.9 | (0.6 - 1.2) | 0.38 |
1Adjusted for race/ethnicity and age.
FDR: First-Degree Relative; HL: Hodgkin's Lymphoma; BC: Breast Cancer.