Table 2: Risk of breast cancer in female Hodgkin's patients and their relatives, 1966-20141

Comparison Breast Cancer HR 95% CI P
Baseline BC risk in FDR of BC patients in Utah 1.8 (1.7-1.8) < 0.0001
Risk in HL patients vs. controls
BC risk in HL patients when BC in FDR 3.8 (1.9-7.7) 0.0003
BC risk in HL patients when no BC in FDR 1.7 (1.2-2.5) 0.002
Risk in HL patients only
HL with BC in FDR vs. HL with no BC in FDR 3.3 (1.6-7.1) 0.002
HL with BC in FDR vs. HL with no BC in FDR, for HL diagnosed 1966-1999 3.7 (1.7-7.9) < 0.001
Risk in FDR of HL vs. FDR of controls:
FDR of HL patients with BC 2.8 (1.4-5.6) 0.005
FDR of HL diagnosed 1966-1999 with BC 2.9 (1.4-5.9) 0.003
FDR of HL patients with no BC 1 (0.8-1.4) 0.97
FDR of HL diagnosed 1966-1999 with no BC 0.9 (0.6 - 1.2) 0.38

1Adjusted for race/ethnicity and age.

FDR: First-Degree Relative; HL: Hodgkin's Lymphoma; BC: Breast Cancer.