Table 2: Association of alleles with creatinine-adjusted cadmium concentration.

 

P-value

Locus (N missing)

Gene and coordinates*

Alleles or haplotypes

Log2-transformed

Not transformed

rs352038 (6)

CXCL3 4:74052981

C/T

0.58

0.74

rs2234693

ESR1 6:151842200

C/T

0.18

0.44

rs9340799

ESR1 6:151842246

A/G

0.99

0.45

rs3020314

ESR1 6:151949537

C/T

0.62

0.64

rs1255998

ESR2 14:64227153

C/G

0.76

0.77

rs944050

ESR2 14:64233327

A/G

0.47

0.97

rs4775936 (12)

CYP19A1 15:51243825

C/T

0.34

0.05

rs28366003 (6)

MT2A 16:56608579

A/G

0.15

0.10

rs3918249 (9)

MMP9 20:46009497

C/T

0.59

0.29

rs12011793

AR X:67698249

C/T

0.48

0.62

rs12011518

AR X:67713194

G/T

0.94

0.88

ESR1Hap§

 

CAC

0.14

0.02

 

CAT

0.74

0.14

 

CGC

0.83

0.65

 

CGT

0.17

0.26

 

TAC

0.44

0.51

 

TAT

0.70

0.47

 

TGC

0.94

0.85

 

TGT

0.06

0.10

ESR2Hapd

 

CA

0.46

0.82

 

GA

0.47

0.18

 

GG

0.22

0.74

ARHapd

 

CG

0.67

0.54

 

CT

0.87

0.58

 

TG

0.35

0.73

 

TT

-

-

*Chromosome number: Position in bp based on Genome Reference Consortium Human Build 38 patch release 7 [29]. †Independent group t-test; ‡Analysis of variance; §Haplotype based on the SNPs located within the corresponding gene.