Table 3: Molecular findings of 105 uterine cancers.
|
No. |
(%) |
|
|
KRAS 12/13 |
|
|
|
Mutated |
19 |
(18.1) |
|
Wild |
86 |
(81.9) |
|
Microsatellite |
|
|
|
Unstable-high |
26 |
(24.8) |
|
Stable |
79 |
(75.2) |
|
Methylation |
|
|
|
Yes |
22 |
(84.6) |
|
No |
4 |
(15.4) |
|
APC* |
|
|
|
LOH† |
6 |
(7.6) |
|
Wild type |
73 |
(92.4) |
|
PTEN* |
|
|
|
LOH |
30 |
(38) |
|
Wild type |
49 |
(62) |
|
PTEN |
|
|
|
Mutated |
21 |
(20) |
|
Wild type |
84 |
(80) |
*26 cancers uninformative because of microsatellite instability.
† Loss of Heterozygosity