Animal models of depression and their criteria for validity.

Table 2: Animal models of depression and their criteria for validity.

Model	Criteria
	Face	Construct	Predictive
Forced swim test (FST)	-	-	+
Tail suspension test (TST)	-	-	+
Chronic unpredictable mild stress (CUMS)	+	+	+
Chronic social isolation stress (CSIS)	+	+	+
Chronic social defeat stress (CSDS)	+	+	+
Learned helplessness (LH)	+	+	+
Maternal deprivation Stress	+	+	+
Olfactory bulbectomy	+	+	+
Lipopolysaccharide	+	+	+
Sub-chronic variable stress (SCVS)	+	+	+

-: Negative; +: Positive.