Table 5: This Table Summarizes A Study That Assessed The Pharmacokinetic Properties Of Ketamine.
| Species | metabolites | References | ||
| Serum | mPFC | Hippocampus | ||
| SD Rats | Females had higher serum NK levels 30 min after administration | Females had higher levels of ketamine & NK than males | Females had higher levels of ketamine & NKT than males | [100] |
| Males had higher serum DHNK levels after 10 & 30 min | ||||
| C57BL6/J | 10 & 3 mg/kg post LPS (0.5 mg/kg) injection, both sexes had similar levels | 10 & 3 mg/kg post LPS (0.5 mg/kg) injection, both sexes had similar levels | [56] | |
NK: Norketamine; DHNK: Dehydronorketamine.