Table 1: Durations of action of different insulin preparations

Insulin preparation Onset (h) Peak (h) Duration (h)
Rapid-acting Insulin analogues: lispro, aspart, glulisine < 0.5 0.5 2.5 3 4.5
Short-acting Regular, soluble insulin 0.5 1 1 4 4 8
Intermediate-acting Isophane (NPH), lente 1 3 3 8 7 14
Long-acting Bovine ultralente 2 4 6 12 12 30
Insulin analogues: glargine, detemir 1 2 None 18 24


These are classified into rapid-, short-, intermediate- and long-acting insulin [3]