Table 1: Durations of action of different insulin preparations

Insulin preparation Onset (h) Peak (h) Duration (h)
Rapid-acting Insulin analogues: lispro, aspart, glulisine < 0.5 0.5 – 2.5 3 – 4.5
Short-acting Regular, soluble insulin 0.5 – 1 1 – 4 4 – 8
Intermediate-acting Isophane (NPH), lente 1 – 3 3 – 8 7 – 14
Long-acting Bovine ultralente 2 – 4 6 – 12 12 – 30
Insulin analogues: glargine, detemir 1 – 2 None 18 – 24


These are classified into rapid-, short-, intermediate- and long-acting insulin [3]