Table 2: Kidney weight (g) with respect to different treatment with A. africanus aqueous extract (EAA) and metformin in diabetic rats.
|
Absolute kidney weight [g] |
p-value |
Relative kidney weight [%] |
p-value |
Neg. control |
1.84 ± 0.10 |
|
0.98 ± 0.19 |
|
Nor. control |
1.35 ± 0.15 |
0.005 |
0.48 ± 0.36 |
< 0.0001 |
Pos. control |
1.52 ± 0.13a |
0.088 |
0.54 ± 0.046a |
< 0.0001 |
EAA 250 mg/kg |
1.59 ± 0.19aA |
0.261 |
0.58 ± 0.05aA |
< 0.0001 |
EAA 500 mg/kg |
1.49 ± 0.19aA |
0.060 |
0.56 ± 0.04aA |
< 0.0001 |
EAA 1000 mg/kg |
1.48 ± 0.21aA |
0.031 |
0.56 ± 0.05aA |
< 0.0001 |
|
F (5, 19) = 3.90; P = 0.013 |
|
F (5, 19) = 16.23; P < 0.0001 |
|
The P values indicate the difference compared to the Neg. control. Lower cases letters of the alphabet indicate the comparison between Pos. control vs. EAA (250, 500, 1000 mg/kg). Upper cases letters of the alphabet indicate the difference between the three doses of the extract (250, 500, 1000 mg/kg). Same letters indicate insignificant difference.