Table 2: Kidney weight (g) with respect to different treatment with A. africanus aqueous extract (EAA) and metformin in diabetic rats.

 

Absolute kidney weight [g]

p-value

Relative kidney weight [%]

p-value

Neg. control

1.84 ± 0.10

 

0.98 ± 0.19

 

Nor. control

1.35 ± 0.15

0.005

0.48 ± 0.36

< 0.0001

Pos. control

1.52 ± 0.13a

0.088

0.54 ± 0.046a

< 0.0001

EAA 250 mg/kg

1.59 ± 0.19aA

0.261

0.58 ± 0.05aA

< 0.0001

EAA 500 mg/kg

1.49 ± 0.19aA

0.060

0.56 ± 0.04aA

< 0.0001

EAA 1000 mg/kg

1.48 ± 0.21aA

0.031

0.56 ± 0.05aA

< 0.0001

 

F (5, 19) = 3.90; P = 0.013

 

 

F (5, 19) = 16.23; P < 0.0001

 

 

The P values indicate the difference compared to the Neg. control. Lower cases letters of the alphabet indicate the comparison between Pos. control vs. EAA (250, 500, 1000 mg/kg). Upper cases letters of the alphabet indicate the difference between the three doses of the extract (250, 500, 1000 mg/kg). Same letters indicate insignificant difference.