Table 2: Association between endothelin-1 and others parameters

Unadjusted	Age-adjusted
Variables	Coefficient (ß)	Std. Err.	P value	Coefficient (ß)	Std. Err.	P value
Age (years)	0.0197	0.0071	0.007	-	-	-
BMI (kg/m2)	-0.0082	0.0209	0.696	-0.0030	0.0207	0.884
Waist circumference (cm)	0.0218	0.0030	0.029	0.0215	0.0098	0.029
Fasting plasma glucose (mmol/L)	0.1057	0.0198	< 0.001	0.1021	0.0196	< 0.001
Triglycerides (mg/dl)	0.0003	0.0006	0.631	0.0003	0.0006	0.667
HDL-C (mg/dl)	-0.0121	0.0051	0.018	-0.0122	0.0049	0.016
Systolic blood pressure (mmHg)	0.0069	0.0038	0.075	0.0045	0.0039	0.254
Diastolic blood pressure (mmHg)	0.0100	0.0084	0.234	0.0041	0.0086	0.635
Total Cholesterol (mg/dl)	-0.0002	0.0011	0.840	-0.0001	0.0011	0.893
LDL-C (mg/dl)	0.0013	0.0012	0.269	0.0012	0.0011	0.314
HOMA-IR	0.0446	0.0272	0.104	0.0472	0.0265	0.077
Insulin (µU/ml)	-0.0017	0.0052	0.737	0.00005	0.0050	0.992

BMI: Body Mass Index, HDL-C: High-Density Lipoprotein Cholesterol, LDL-C: Low-Density Lipoprotein Cholesterol, HOMA-IR: Homeostasis Model Assessment of Insulin Resistance.