Table 5: Comparison of Studies of Lifestyle Intervention vs Pharmacological Agents

Study	Intervention		N	Duration (yrs.)	Risk Reduction (%)	Follow up time (yrs.)	Follow up risk reduction (%)	CVD events/Total mortality reduction (%)
Lifestyle Intervention studies
Da Qing [8,9]	Diet Exercise Diet and Exercise Control		130 141 126 133	6	31 46 42	20	43	2/4
DPS Finland [10,20]	Diet and Physical Activity Control		265 257	3.2	58	7	43	4/43
DPP US [11]	Diet and Physical activity Metformin Placebo		1079 1073 1082	2.8	58 31	10	34	No Data
Pharmacological Intervention studies
DPP US [11]	Metformin	1073		2.8	31	10	18	No Data
TRIPOD [23]	Troglitazone	236		2.5	55
STOP-NIDDM [17,18]	Acarbose	1368		3.2	36	NA	NA	49
DREAM [14]	Rosiglitazone	5269		3.0	60	NA	NA	No Data
XENDOS [24]	Orlistat	3305		4.0	37	NA	NA	No Data