Table 3: Clinical and biochemical parameters before and after intensive insulin intervention.

 

Before insulin intervention

After insulin intervention

p-value

Number of Subject (n)

15

15

 

Systolic blood pressure (mmHg)

119.6 ± 12.6

122.3 ± 11.1

0.38

Diastolic blood pressure (mmHg)

74.1 ± 8.4

76.4 ± 6.7

0.13

Weight (Kg)

73.3 ± 14.1

75.2 ± 13.6

0.02

Body mass index (Kg/m2)

26.4 ± 3.9

27.0 ± 3.5

0.03

Waist circumference (cm)

89.5 ± 8.6

91.0 ± 7.6

0.01

Hip Circumference (cm)

108.8 ± 8.6

108.8 ± 10.3

0.98

Waist/Hip ratio

0.81 ± 0.14

0.83 ± 0.05

0.008

Fat mass (Kg)

23.1 ± 7.1

28.2 ± 6.4

< 0.001

Percent body fat (%)

31.3 ± 6.6

21.2 ± 6.3

< 0.001

Free fat mass (%)

50.2 ± 9.7

54.0 ± 10.6

< 0.001

Insulin sensitivity (%/minute)

1.98 ± 0.23

2.26 ± 0.18

< 0.001

Fasting capillary glycemia (mg/dL)

385.4 ± 98.6

134.4 ± 18.2

< 0.001

Total cholesterol (g/L)

1.68 ± 0.25

1.52 ± 0.30

< 0.001

Triglyceride (g/L)

1.08 ± 0.55

1.05 ± 0.46

0.71

HDL cholesterol (g/L)

0.64 ± 0.33

0.68 ± 0.32

0.30

LDL cholesterol (g/L)

0.83 ± 0.36

0.62 ± 0.37

< 0.001

Urine glucose (mg/dL)

313.3 ± 310.2

00.00

0.002