Table 4: Comparison of the laboratory characteristics of the subjects with OHA failure and those without OHA failure.          

Variable

OHA failure

No OHA failure

(p-value)

Mean (SD)

Mean (SD)

FPG (mmol/L)

11.7 (2.6)

5.7 (1.5)

(0.000)*

2hrPPG (mmol/L)

14.5 (3.7)

11.1 (2.8)

(0.000)*

Tc (mmol/L)

4.98 (0.9)

5.12 (0.9)

-0.572

LDL-c (mmol/L)

3.8 (0.9)

4.1 (1.0)

-0.254

HDL-c (mmol/L)

0.74 (0.3)

0.69 (0.2)

-0.381

Tg (mmol/L)

0.95 (0.3)

1.1 (0.3)

-0.7

HbA1c (%)

8.3 (1.4)

7.0 (2.1)

(0.003)*

C-peptide

0.84 (0.05)

1.72 (0.43)

(0.002)*

 

OHA = Oral hypoglycaemic agent, FPG = Fasting plasma glucose, 2hrPPG = Two hours post prandial glucose, Tc = Total cholesterol, LDL-c = Low density lipoprotein cholesterol, HDL-c= High density lipoprotein cholesterol, Tg = Triglycerides, HbA1c = Glycated haemoglobin A1c, * = Significant p value