Table 3: Group comparisons of metabolic parameters at different time points adjusting for covariates.
4000 IU (n = 50) | 6000 IU (n = 25) | |
25(OH)D (ng/ml) | ||
Baseline | 22.25 ± 7.19 | 23.74 ± 5.09 |
3 months | 37.34 ± 12.31* | 43.20 ± 15.94* |
6 months | 37.99 ± 13.22* | 40.62 ± 19.39* |
P-value groups = 0.232 | P-value time = 0.019 | P-value interaction = 0.352 |
Total Cholesterol (mg/dl) | ||
Baseline | 213.08 ± 42.30 | 193.88 ± 41.03 |
3 months | 209.26 ± 43.62 | 184.68 ± 50.89 |
6 months | 199.84 ± 32.79 | 180.48 ± 27.53 |
P-value groups = 0.204 | P-value time = 0.954 | P-value interaction = 0.605 |
Triglycerides (mg/dl) | ||
Baseline | 182.98 ± 110.11 | 201.44 ± 91.35 |
3 months | 174.62 ± 109.83 | 192.20 ± 94.49 |
6 months | 187.08 ± 151.26 | 172.92 ± 76.87 |
P-value groups = 0.962 | P-value time = 0.250 | P-value interaction = 0.167 |
LDL Cholesterol | ||
Baseline | 128.34 ± 40.54 | 115.56 ± 34.53 |
3 months | 125.88 ± 40.90 | 120.00 ± 35.37 |
6 months | 120.76 ± 30.35 | 121.96 ± 40.60 |
P-value groups = 0.969 | P-value time = 0.872 | P-value interaction = 0.423 |
HDL Cholesterol | ||
Baseline | 50.64 ± 12.20 | 42.44 ± 10.40 |
3 months | 48.92 ± 11.12 | 42.12 ± 12.35 |
6 months | 46.98 ± 10.37 | 42.12 ± 12.76 |
P-value groups = 0.088 | P-value time = 0.188 | P-value interaction = 0.118 |
Data represented by mean ± standard error. *Represents significant differences from baseline. Level of significance is at P < 0.05.
25(OH)D: serum vitamin D; LDL: low density lipoprotein; HDL: high density lipoprotein; Analysis was adjusted for age, gender,
years with diabetes, smoking, BMI, vitamin D intake, sun exposure score, fasting plasma glucose, upper arm skin color, forearm skin color, and lipid lowering medication use.