Table 6: Effect of ARBs and antidiabetic agents on electrolytes during 3 consecutive follow ups.

Parameters Na (MMOL/L) Cl (MMOL/L) K (MMOL/L)
Antihypertensive agents Antidiabetic agents 1st 2nd 3rd 1st 2nd 3rd 1st 2nd 3rd
ARBs Insulin 136.5a ± 0.7 137.8 ± 0.8 137 ± 0.7 102.6 ± 0.7 103.8 ± 0.7 102.6 ± 0.7 4.3 ± 0.1 4.3a ± 0.1 4.3a ± 0.1
Biguanide 138 ± 0.5 139.3 ± 0.6 137.8 ± 0.9 104 ± 0.4 103.5 ± 0.5 102 ± 0.6 4.1 ± 0.1 3.8b ± 0.1 4.0b ± 0.1
Biguanide + DPP-4 139b ± 0.8 137.8 ± 0.5 139 ± 0.7 104 ± 0.5 102.8 ± 0.5 102.9 ± 0.5 4.2 ± 0.1 4.1 ± 0.0 4.1 ± 0.0

Values represent mean ± SE.
Different Small alphabetical letters in the same column within the same parameters are significant at P < 0.05 (Two way ANOVA).