Table 1: Demographic and clinical characteristics of Type 1 vs. Type 2 patients at admission to INDEN's pediatric clinic between 2000 and 2016.

 

Total Population N (%) or Mean ± SD

(n = 874)

Type 1

N (%) or Mean ± SD (n = 696)

Type 2

N (%) or Mean ± SD (n = 178)

P-value

Age (years)

10.95 ± 4.14

10.43 ± 4.24

13.27 ± 2.67

< 0.0001

Sex (% Female)

489 (56.08)

373 (53.67)

116 (65.54)

0.0045

Resides within Santo

Domingo Province

483 (56.82)

367 (54.29)

116 (66.67)

0.0033

Family history

 

 

 

 

First degree (parent, sibling)

185 (21.29)

96 (13.89)

89 (50.00)

< 0.0001

Second degree (grandparent)

404 (46.49)

299 (43.27)

105 (58.99)

0.0002

Overweight or obese (WHO

categorization)

317 (46.08)

191 (36.94)

126 (73.68)

< 0.0001

Duration of diabetes (years)

3.15 ± 3.26

3.43 ± 3.45

2.07 ± 2.04

0.0003

Average Annual Visit

Frequency

3.17 ± 1.36

3.14 ± 1.38

3.30 ± 1.23

0.0051

Hospitalized

331 (38.44)

292 (42.63)

39 (21.16)

< 0.0001

Hypoglycemic episodes (as a

patient)

393 (45.02)

333 (47.91)

60 (33.71)

< 0.0001

Ketoacidosis episodes (as a

patient)

98 (11.40)

90 (13.14)

8 (4.57)

0.0015

Two or more episodes of

hospitalization, hypoglycemia, or ketoacidosis

46 (5.65)

42 (6.53)

4 (2.34)

0.0348

Lost to follow up

560 (64.15)

441 (63.45)

119 (66.85)

0.4066

Self-monitoring

324 (37.72)

273 (39.68)

51 (29.82)

< 0.0221

HbA1c % (mmol/mol)

9.86 ± 3.14

9.94 ± 3.17

9.57 ± 3.02

0.3988

Cholesterol (mg/dL)

167.99 ± 43.87

169.65 ± 44.00

161.39 ± 42.94

0.0839

Triglycerides (mg/dL)

90.96 ± 75.21

85.72 ± 71.44

111.74 ± 85.90

0.0002

HDL (mg/dL)

50.08 ± 16.60

52.10 ± 16.72

43.03 ± 14.13

< 0.0001

LDL (mg/dL)

101.69 ± 38.84

103.35 ± 38.25

95.83 ± 40.61

0.1190

c-peptide (ng/mL)

0.90 ± 1.04

0.64 ± 0.88

1.66 ± 1.10

< 0.0001

Anti-GAD (un/mL)

20.42 ± 32.01

21.50 ± 32.58

1

0.2613

Anti-ICA

31.88 ± 31.95

35.71 ± 32.46

5

0.2575

Comorbidities

 

 

 

 

Hypertension

2 (0.23)

2 (0.29)

0

N/a

Asthma

36 (4.12)

31 (4.45)

5 (2.81)

N/a

Thyroid disease

50 (5.72)

41 (5.89)

9 (5.06)

N/a

Polycystic ovary

7 (0.80)

4 (0.57)

3 (1.69)

N/a

Gastroparesis

2 (0.23)

2 (0.29)

0

N/a

BMI: Body Mass Index; HbA1c: Hemoglobin A1c; HDL: High-Density Lipoprotein; LDL: Low-Density Lipoprotein; Anti-GAD: Anti-Glutamic Acid Decarboxylase Antibody; Anti-ICA: Antibodies Against Islet Cells; Categories may not sum to total due to missing values; One patient may have more than one comorbidity.