Table
3: A meta-analysis
pooling odds ratios for cutaneous melanoma and dose information for continuous
or ordered categorical factors across case-control studies in populations of
Spanish descent based on a random effects model.
Linear Dose-Response Analysesa |
Crude |
Heterogeneity |
Adjusted |
Heterogeneity |
|||||
N |
OR |
95% CI |
p-value |
I2 |
OR |
95% CI |
p-value |
I2 |
|
Skin Type - a difference of |
3 |
0.016 |
75.70% |
0.034 |
70.40% |
||||
1 (I vs. II, II vs. III, or III vs. IV) |
2.34 |
2.00-2.75 |
2.31 |
1.95-2.74 |
|||||
3 (I vs. IV) |
12.87 |
7.95-20.82 |
12.35 |
7.43-20.51 |
|||||
Lifetime sunburns - a difference ofb |
3 |
0.01 |
78.50% |
0.008 |
79.30% |
||||
1 burn per lifetime |
1.14 |
1.11-1.18 |
1.1 |
1.07-1.14 |
|||||
5 burns per lifetime |
|
1.95 |
1.69-2.24 |
|
|
1.62 |
1.38-1.91 |
|
|
CI =
Confidence interval, N = Number of subjects, OR = Odds ratios, vs = versus.
aA
linear model estimates an increase of one unit, but can be set to specific
units while remaining the same model. We present a difference that is
meaningful for a given factor.
bAn
upper limit of the number of sunburns was estimated from which the median of
the upper category for each