Table
2: FISH findings for the 20 metastatic
melanomas. Specimens were designated FISH positive if at least one of four
criteria listed in table 4 were met. Values rendering a FISH positive result
are highlighted in bold.
|
Subject |
Mean
RREB1 |
RREB1
% abnormal (n/60) |
Mean
MYB |
MYB
% loss (n/60) |
Mean
CCND1 |
Mean
CEP6 |
FISH
Result |
|
M1 |
2.90 |
80.0%
(48/60) |
1.50 |
13.5%
(8/60) |
2.45 |
1.18 |
+ |
|
M2 |
2.75 |
50.0%
(30/60) |
2.23 |
42%
(25/60) |
2.47 |
2.38 |
+ |
|
M3 |
2.22 |
33.0%
(20/60) |
1.20 |
58%
(35/60) |
2.08 |
1.92 |
+ |
|
M4 |
2.43 |
53.0%
(32/60) |
1.67 |
10.5%
(6/60) |
1.72 |
1.54 |
- |
|
M5 |
4.30 |
93.5%
(56/60) |
2.23 |
36.5%
(22/60) |
2.20 |
2.55 |
+ |
|
M6 |
3.67 |
88.5%
(53/60) |
3.08 |
20%
(12/60) |
2.94 |
2.94 |
+ |
|
M7 |
3.83 |
93.5%
(56/60) |
1.42 |
70% (42/60) |
1.97 |
2.62 |
+ |
|
M8 |
4.03 |
90.0%
(54/60) |
2.38 |
76.5% (46/60) |
3.23 |
3.52 |
+ |
|
M9 |
2.84 |
71.5%
(43/60) |
1.47 |
65%
(39/60) |
2.18 |
2.70 |
+ |
|
M10 |
2.62 |
58.3%
(35/60) |
2.30 |
13.5%
(8/60) |
3.28 |
2.10 |
+ |
|
M11 |
3.45 |
81.7%
(49/60) |
2.39 |
8.64%
(5/60) |
2.42 |
2.35 |
+ |
|
M12 |
2.75 |
72.0%
(43/60) |
1.55 |
25.3%
(15/60) |
2.92 |
2.12 |
+ |
|
M13 |
3.59 |
83.5%
(50/60) |
1.75 |
35.17%
(21/60) |
2.37 |
2.38 |
+ |
|
M14 |
2.60 |
70.0%
(42/60) |
0.98 |
6.82%
(4/60) |
2.37 |
1.99 |
+ |
|
M15 |
2.87 |
78.5%
(47/60) |
1.64 |
21.72%
(13/60) |
1.78 |
1.97 |
+ |
|
M16 |
3.77 |
52.4%
(31/60) |
2.18 |
13.77%
(8/60) |
3.17 |
3.35 |
+ |
|
M17 |
3.60 |
79.8%
(48/60) |
1.68 |
31.72%
(19/60) |
1.87 |
2.77 |
+ |
|
M18 |
4.05 |
95.0%
(57/60) |
1.68 |
45.25%
(27/60) |
2.17 |
2.82 |
+ |
|
M19 |
2.60 |
49.1%
(29/60) |
1.89 |
14.04%
(8/60) |
2.02 |
2.19 |
- |
|
M20 |
3.17 |
83.33%
(50/60) |
2.70 |
30.00%
(18/60) |
2.33 |
2.73 |
+ |