Timeline of unsuccessful interventions before treatment with transfer factors.

Table 1: Timeline of unsuccessful interventions before treatment with transfer factors.

Date	Previous interventions to the treatment
August 2017	One treatment of electrocoagulation.
September - October 2017	Two treatments of cryotherapy, including home use of urea 40% + salicylic acid 2% topical cream (once daily for the whole period).
Late October 2017 - early January 2018	Imiquimod 5% topical cream (3-times a week) and oral zinc (20 mg/day, once daily).
January 2018	One treatment of cryotherapy.
January 2018 - April 2018	One treatment of cryotherapy and home use of salicylic acid 16.5% + lactic acid 14.5% solution (3-times per week), alternated with retinoic acid 0.1% cream (3-times per week).
May 2018	One treatment of cryotherapy.
May - July 2018	Homeopathy with Thuya occidentalis 30CH, 5 globuli (3-times daily) and fluorouracil 0.5% + salicylic acid 10% + lactic acid 5% cream (3-times per week).
August 2018	One treatment of cryotherapy.
August - October 2018	L-lysine 500 mg (3-times daily, with the meal).
September 2018	Intralesional bleomycin (3 IU).