Table 1:
Cytotoxic effect of CD8+ cells expanded in PBL IVC.
Functional characterization of expanded CD8+ Mart-1 antigen specific cells expanded in
PBL + autologous tumor IVCs by cytotoxicity assays using autologous and allogeneic tumor cells as targets.
Effector cells from PBL + Tumor IVC from patient |
Target cells | 40:1 | 20:1 | 10:1 |
UC-1 | UC-1 Tumor | 52 | 30 | 22 |
UC-1 | Allo-Tumor | 0 | 0 | 0 |
UC-2 | UC-2 Tumor | 38 | 25 | 20 |
UC-2 | Allo Tumor | 10 | 10 | 5 |
UC-3 | UC-3 Tumor | 44 | 28 | 18 |
UC-3 | Allo-Tumor | 0 | 0 | 0 |
UC-4 | UC-4 Tumor | 58 | 35 | 30 |
UC-4 | Allo Tumor | 0 | 0 | 0 |
UC-5 | UC-5 Tumor | 60 | 30 | 22 |
UC-5 | Allo-Tumor | 0 | 0 | 0 |
UC-6 | UC-6 Tumor | 48 | 35 | 25 |
UC-6 | Allo Tumor | 12 | 10 | 5 |