Table 2:
Fate of induced CD8+ CTLs generated with PBL in cultures with autologous tumors or Mart-1 peptide pulsed DC.
"+" = Cytokine secreted more than 50 pg and cytotoxic effect more than 20% killing of the target cells with highest Effector cells: target cells.
"++" = Cytokine secreted more than 100 pg/ml and cytotoxic effect more than 40% with highest Effector: target cells. "-" = No cytokine or no cytotoxic effect.
Cytokine production | Cytolytic function | ||||||
Day 7 | Day 14 | Day 21 | Day 28 | Day 7 | Day 14 | Day 21 | Day 28 |
+ | ++ | + | - | ++ | ++ | + | - |