Table 4: Effect of total flavonoids extract of P. kotschyi on total blood leukocyte and differential leukocytes blood count in horse serum-induced anaphylaxis in rats.
Parameters |
Negative Xontrol |
Sensitized Control |
Positive Control |
50 mg/kg TFE |
100 mg/kg TFE |
TWBC (Cells/ml) |
4714 ± 457.08a |
10724 ± 698.48b |
6148 ± 612.26***† |
8346 ± 937.19***‡ |
7476 ± 1022.46***† |
Lymphocyte (%) |
64.29 ± 7.19a |
28.78 ± 3.11b |
59.77 ± 1.08***† |
40.85 ± 1.68**‡ |
52.2 ± 6.8***† |
Monocyte (%) |
1.73 ± 1.34a |
10.12 ± 1.19b |
4.46 ± 0.80**‡ |
10.53 ± 1.03‡ |
10.03 ± 3.73‡ |
Neutrophil (%) |
29.65 ± 4.46a |
37.77 ± 1.53b |
27.45 ± 1.71***† |
32.39 ± 1.71† |
26.26 ± 4.15***† |
Eosinophil (%) |
1.77 ± 0.52a |
21.26 ± 2.08b |
7.03 ± 1.27***† |
15.33 ± 1.63***‡ |
8.97 ± 2.76***† |
**p < 0.01, *** p < 0.001 compared with sensitized control; a, b) P < 0.05 denote significance difference between negative control and sensitized control; ‡, † P < 0.05 denote significance difference positive control and treated rats.