Table 7: GDF5 genotypes and functional disability in KOA.
|
Kellgren Score: |
|
|
TT (15) |
TC (26) |
CC (9) |
X2 |
P |
|||
|
No |
% |
No |
% |
No |
% |
No |
% |
3.7139 |
0.715 |
|
|
Grade 0 |
4 |
6 |
1 |
25 |
2 |
50 |
1 |
25 |
||
|
Grade I |
17 |
36 |
6 |
35.2 |
8 |
47.1 |
3 |
17.6 |
||
|
Grade II |
21 |
44 |
6 |
28.5 |
13 |
61.9 |
2 |
9.5 |
||
|
Grade III |
8 |
14 |
2 |
25 |
3 |
37.5 |
3 |
37.5 |
||
|
Lequesne Index for Activity |
||||||||||
|
Mild 1-4 |
17 |
34 |
7 |
41.2 |
8 |
47 |
2 |
11.8 |
4.72 |
0.79 |
|
Moderate 5-7 |
16 |
32 |
3 |
18.8 |
10 |
62.5 |
3 |
18.7 |
||
|
severe 8-10 |
5 |
10 |
1 |
20 |
2 |
40 |
2 |
40 |
||
|
Very severe 11-13 |
9 |
18 |
3 |
33.3 |
5 |
55.6 |
1 |
11.1 |
||
|
Extremely severe ≥ 14
|
3
|
6
|
1
|
33.3
|
1
|
33.3
|
1
|
33.3
|
||
|
Womac OA Index |
||||||||||
|
Less severe ≤ median (25) |
22 |
44 |
7 |
31.8 |
10 |
45.5 |
5 |
22.7 |
0.854 |
0.65 |
|
More severe > median (25) |
28 |
56 |
8 |
28.6 |
16 |
57.1 |
4 |
14.3 |
||