Table 3: Level of cytokines IL-6, TNF-α and TGF-β1 in rats after induction of diabetic with Streptozotocin compared to control group.
Parameters
% of change |
Control
(Non-diabetic) |
Streptozotocin
70 mg/kg body weight
(Diabetic rats) |
IL-6 (pg/ml) |
230.64 ± 5.2 |
420.34 ± 6.2*** |
% of change |
82.24% |
|
TNF-α (pg/ml) |
180.24 ± 2.5 |
320.45 ± 3.3*** |
% of change |
77.7% |
|
TGF-β1 (pg/ml) |
160.52 ± 2.8 |
280.63 ± 4.1*** |
% of change |
74.50% |
***Significantly different from control at p < 0.001.