Table 2: Clinical Features of 10 Filipino genetically-positive SCA2 patients (N = 10).
|
|
Number of Patients (Percentage) |
|
Motor Cerebellar Manifestations |
|
|
Gait ataxia |
9 (90%) |
|
Postural instability |
9 (90%) |
|
Cerebellar dysarthria |
10 (100%) |
|
Dysmetria |
8 (80%) |
|
Dysdiadochokinesia |
7 (70%) |
|
Oculomotor Disturbances |
5 (50%) |
|
Extrapyramidal Features |
|
|
Resting tremors |
2 (20%) |
|
Bradykinesia |
3 (30%) |
|
Rigidity |
2 (20%) |
|
Dyskinesias |
2 (20%) |
|
Peripheral Neuropathy Manifestations |
|
|
Paresthesias |
5 (50%) |
|
Hypoesthesia |
1 (10%) |
|
Hyperesthesia |
1 (10%) |
|
Sleep Disorders |
5 (50%) |
|
Cognitive Decline |
5 (50%) |
|
Autonomic Dysfunction |
1 (10%) |