Gene Symbol

Gene Name

Fold Change

Function

Il27

Interleukin 27

-5.69

Cytokine that is known to synergize with IL12B to trigger IFNG production

Il23a

Interleukin 23 Subunit Alpha

-4.00

Cytokine that is important part of the inflammatory response against infection

Gdf15

Growth Differentiation Factor 15

-3.69

Ligand of the TGF-beta super-family that regulates inflammatory pathways

Dmd

Dystrophin

-3.40

Cytoskeletal protein in muscle cells that provides for tensile strength

Nr4a3

Nuclear Receptor Subfamily 4 Group A Member 3

-3.38

Protein that is a member of the thyroid hormone receptor and may act as a transcriptional activator

Mir155hg

MicroRNA Host Gene 2

-3.22

Non-protein coding microRNA

Dusp8

Dual Specificity Phophatase 8

-3.13

Phosphatase that negatively regulates members of the MAP kinase family.

Nfkbiz

NF-Kappa-B Inhibitor Zeta

-2.91

Plays a role in inflammatory responses to LPS

Chac1

Glutathione-specific Gamma-glutamylcyclotransferase 1

-2.90

Catalyzes the cleavage of glutathione

Gm40447

Predicted Gene 40447

-2.88

No known function at this time

Ptprd

Receptor-type Tyrosine-protein Phosphatase delta

-2.85

Involve in neuronal differentiation and may act as a tumor suppressor

Sstr5

Somatostatin Receptor Type 5

-2.76

May increase cell growth inhibition

Tnfsf9

Tumor Necrosis Factor Ligand Superfamily 9

-2.75

Cytokine that Induces proliferation of activated peripheral blood T-cells

Ddit4

DNA Damage-inducible Transcript 4 Protein

-2.66

Regulates cell growth, proliferation and survival via inhibition of mTORC1

Phlda1

Pleckstrin Homology-like Domain Family A1

-2.64

Mediates apoptosis via increased sensitivity to chemotherapeutic agents