Table 4: Fold change of the Top 10 most down-regulated genes following treatment of BV2 microglia cells with FL-ApoE4 and their fold change following treatment with nApoE41-151 (p < 0.05).

Decrease

FL E4

E4 Fragment

Il27

-5.69

183

Il23a

-4.00

14.1

Gdf15

-3.69

18.6

Dmd

-3.40

-

Nr4a3

-3.38

6.42

Mir155hg

-3.22

68.2

Dusp8

-3.13

45.6

Nfkbiz

-2.91

16.1

Chac1

-2.90

3.57

Gm40447

-2.88

6.93