Author/year | Cases (No) | Responders (No) | Stimulationcycleused | Frequency | Mean follow-up (months) | Conclusions |
Scherrmann J et al. 2001 [2] | 95 | 38 | 7 sec on/30 sec off 30 sec on/5 min off |
20 Hz 30 Hz |
15.8 ± 10.3 | Better outcome in patients with stimulation-on period of 30 sec |
DeGiorgio CM et al. 2001 [3] | 154 | NR | 12-66 sec off/7-60 sec on 1.8 min off/7-60 sec on 3 min off/7-60 sec on 5 min off/7-60 sec on |
30 Hz | 12 | Patients with 30 sec on and 5 min off continue to respond or improve in their response over 1 year period. Some patients may benefit from reductions in off time (increases duty cycle) |
Labar D et al. 2004 [1] | 269 | 153 | > 3 min off (standard cycle) < 1.8 min off(rapid cycle) |
NR | 12 | No differences between standard or rapid cycle |
DeGiorgio C et al. 2005 [4] | 61 | 18 | 7 seconds on/18 seconds off 30 seconds on/30 seconds off 30 seconds on/3 minutes off |
20-30 Hz | 3 | In the first 3 months of therapy, initial setting of 30 seconds on/3 minutes off is well tolerated, and produce the most 75% responders |