Table 2: Results of meta-analysis for ERCC1 C8092A and C118T and the risk of glioma.

Genetic

model

Dominant model

Recessive model

Co-dominant model

Co-dominant model

Additive model

C8092A

AA/AC vs. CC

AA vs. AC/CC

AA vs. CC

AC vs. CC

A vs. C

OR

(95% CI)

Ph

I2 (%)

OR

(95% CI)

Ph

I2 (%)

OR

(95% CI)

Ph

I2 (%)

OR

(95% CI)

Ph

I2 (%)

OR

(95% CI)

Ph

I2 (%)

Total

1.04

(0.94,1.16)

0.586

0

1.51

(1.24,1.85)

0.335

12.6

1.52

(1.24,1.86)

0.37

6.8

0.98

(0.88,1.09)

0.666

0

1.1

(1.02,1.20)

0.558

0

Ethnicity

Chinese

1.12

(0.95,1.33)

0.962

0

1.34

(1.02,1.75)

0.566

0

1.37

(1.03,1.81)

0.65

0

1.06

(0.89,1.27)

0.894

0

1.15

(1.01,1.30)

0.832

0

Caucasian

1.00

(0.88,1.14)

0.281

21.1

1.75

(1.31,2.34)

0.259

25.9

1.70

(1.27,2.29)

0.19

39.7

0.93

(0.82,1.07)

0.418

0

1.08

(0.97,1.19)

0.22

33.9

C118T

TT/CT vs. CC

TT vs. CT/CC

TT vs. CC

CT vs. CC

T vs. C

OR

(95% CI)

Ph

I2 (%)

OR

(95% CI)

Ph

I2 (%)

OR

(95% CI)

Ph

I2 (%)

OR

(95% CI)

Ph

I2 (%)

OR

(95% CI)

Ph

I2 (%)

Total

1.04

(0.89,1.22)

0.478

0

0.99

(0.83,1.19)

0.116

49.2

1.04

(0.84,1.29)

0.12

48.7

1.03

(0.87,1.22)

0.818

0

1.02

(0.91,1.13)

0.119

48.7

 

Abbreviations: Ph: p values for heterogeneity from Q test, random-effects model was used when p values for heterogeneity test < 0.10; otherwise, fixed-effects model was used.