Table 1: Biomarker profiles and categories (modified after [7]).

AT(N) profiles

Biomarker category

 

A–T–(N)–

Normal AD biomarkers

 

A+T–(N)–

Alzheimer’s pathologic change (early stage)

Alzheimer’s
continuum

A+T+(N)–

Alzheimer’s disease

A+T+(N)+

Alzheimer’s disease

A+T–(N)+

Alzheimer’s and suspected non-Alzheimer’s pathologic change (SNAP)

A–T+(N)–

Non-AD pathologic change - other tauopathies

?

A–T–(N)+

Non-AD pathologic change/neurodegenerative disorders

?

A–T+(N)+

Non-AD pathologic change (PART)