Table 3: Morphological diagnoses in consecutive Vienna autopsy series of A) demented and B) clinically diagnosed AD patients.
Morphologic diagnosis |
(A) % |
(B) % |
"Pure" AD (ABC 3/3/3) |
41.1 |
47.6 |
Subtypes of AD (plaque, limbic, PART) |
6.9 |
5.8 |
AD + CVD (lacunar state, old/acute infarcts, AH-sclerosis) |
16.5 |
22.9 |
AD + cerebral hemorrhage (CAA) |
3.1 |
1.9 |
Lewy body variant AD/Diff, LB disease |
3.8 |
3.5 |
AD + Parkinson pathol., PD, Incid. LBD, SN lesions |
5.3 |
6.2 |
MIX type dem, (AD+MIE, +SAE, +SID) |
4.6 |
3.6 |
AD + other pathologies (tumors, MS, MSA, etc.) |
1.6 |
1.2 |
Alzheimer pathology total |
82.9 |
92.8 |
Vascular dementia (MIE, SAE, SID, Ath.scler.) |
10.7 |
3.3 |
Other disorders (Huntington disease, FTD, CJD, others) |
5.5 |
3.1 |
Nothing abnormal beyond age |
0.9 |
0.8 |
Non-Alzheimer pathologies |
17.1 |
7.2 |
Total n (100%) |
1700 |
890 |