Table 4: Spectral domain optical coherence
tomography analysis of pigment epithelial detachment after switching to aflibercept in eyes with refractory neovascular
age-related macular degeneration (n = 36).
|
Baseline median (lower quartile, upper quartile) |
12 weeks median (lower quartile, upper quartile) |
P value |
48 weeks median (lower quartile, upper quartile) |
P value |
PED Height (µm) |
209.5 (111.5, 325.8) |
156 (103, 287) |
P < 0.001 |
157 (85, 229.5) |
P = 0.0002 Student’s t-test P = 0.0002 Wilcoxon signed-rank test |
PED Volume (mm3) |
0.905 (0.57, 2.13) |
0.79 (0.46, 1.10) |
P = 0.003 Student’s t-test P = 0.002 Wilcoxon signed-rank test |
0.67 (0.48, 1.08) |
P = 0.005 Student’s t-test P = 0.001 Wilcoxon signed-rank test |