Table 4: Impact of type of treatment on QOL scores with EORTC QLQ-30 & QLQ H&N-35 questionnaires.
Scales (QLQ-C30) |
CT + RT (n = 8) |
RT (n = 3) |
SX + CT + RT (n = 12) |
SX + RT (n = 50) |
ANOVA P value |
Global health status |
54.17 ± 22.71 |
72.22 ± 25.46 |
64.58 ± 11.31 |
69.50 ± 25.73 |
0.3732 |
Physical functioning |
87.50 ± 12.05 |
84.44 ± 26.94 |
94.44 ± 6.25 |
84.67 ± 16.45 |
0.2668 |
Role functioning |
85.42 ± 16.52 |
83.33 ± 28.87 |
95.83 ± 10.36 |
87.00 ± 23.40 |
0.5806 |
Emotional functioning |
71.88 ± 18.87 |
75.00 ± 36.32 |
88.19 ± 12.54 |
73.00 ± 26.11 |
0.2675 |
Cognitive functioning |
89.58 ± 15.27 |
83.33 ± 28.87 |
95.83 ± 10.36 |
87.00 ± 22.15 |
0.5656 |
Social functioning |
85.42 ± 20.77 |
66.67 ± 44.10 |
91.67 ± 16.67 |
86.67 ± 24.28 |
0.4485 |
Fatigue |
33.33 ± 18.78 |
29.63 ± 27.96 |
25.93 ± 15.95 |
28.00 ± 22.47 |
0.8933 |
Nausea and vomiting |
4.17 ± 7.72 |
5.56 ± 9.62 |
4.17 ± 10.36 |
3.00 ± 8.71 |
0.9352 |
Pain |
22.92 ± 23.46 |
27.78 ± 34.69 |
11.11 ± 14.79 |
17.67 ± 23.67 |
0.5772 |
Dyspnoea |
12.50 ± 24.80 |
0.00 ± 0.00 |
0.00 ± 0.00 |
2.67 ± 9.14 |
0.0794 |
Insomnia |
25.00 ± 34.50 |
33.33 ± 33.33 |
11.11 ± 21.71 |
15.33 ± 22.55 |
0.3789 |
Appetite loss |
25.00 ± 23.57 |
33.33 ± 33.33 |
27.78 ± 39.78 |
18.67 ± 29.48 |
0.6942 |
Constipation |
25.00 ± 15.43 |
11.11 ± 19.24 |
11.11 ± 21.71 |
14.67 ± 23.48 |
0.5638 |
Diarrhoea |
0.00 ± 0.00 |
0.00 ± 0.00 |
2.78 ± 9.62 |
5.33 ± 14.06 |
0.6136 |
Financial difficulties |
41.67 ± 29.55 |
44.44 ± 50.92 |
55.56 ± 32.82 |
56.00 ± 37.16 |
0.7283 |
QLQ H&N-35 |
|||||
Pain |
15.63 ± 13.68 |
41.67 ± 46.40 |
13.19 ± 9.70 |
17.83 ± 21.10 |
0.1933 |
Swallowing |
17.71 ± 12.15 |
30.56 ± 33.68 |
31.94 ± 16.98 |
23.50 ± 22.19 |
0.4470 |
Senses problems |
14.58 ± 13.91 |
16.67 ± 16.67 |
26.39 ± 18.06 |
18.00 ± 20.44 |
0.5107 |
Speech problems |
27.78 ± 23.00 |
33.33 ± 33.33 |
20.37 ± 21.10 |
27.56 ± 23.57 |
0.7548 |
Trouble with social eating |
29.17 ± 30.21 |
27.78 ± 25.46 |
28.47 ± 20.55 |
31.50 ± 30.50 |
0.9835 |
Trouble with social contact |
15.00 ± 25.13 |
22.22 ± 38.49 |
17.78 ± 12.50 |
21.47 ± 25.81 |
0.8899 |
Less sexuality |
25.00 ± 38.83 |
11.11 ± 19.24 |
16.67 ± 18.80 |
19.33 ± 32.01 |
0.9021 |
Teeth |
29.17 ± 27.82 |
22.22 ± 38.49 |
16.67 ± 17.41 |
37.33 ± 32.04 |
0.1753 |
Opening mouth |
33.33 ± 30.86 |
33.33 ± 33.33 |
47.22 ± 26.43 |
42.67 ± 40.43 |
0.8398 |
Dry mouth |
41.67 ± 34.50 |
55.56 ± 38.49 |
52.78 ± 33.21 |
46.67 ± 34.99 |
0.8749 |
Sticky saliva |
25.00 ± 23.57 |
44.44 ± 50.92 |
36.11 ± 36.12 |
29.33 ± 32.74 |
0.7643 |
Coughing |
16.67 ± 17.82 |
22.22 ± 38.49 |
11.11 ± 16.41 |
16.00 ± 19.33 |
0.7971 |
Felt ill |
29.17 ± 27.82 |
33.33 ± 33.33 |
19.44 ± 22.29 |
31.33 ± 31.16 |
0.6575 |
Pain killers |
50.00 ± 53.45 |
33.33 ± 57.74 |
33.33 ± 49.24 |
14.00 ± 35.05 |
0.0840 |
Nutritional supplements |
62.50 ± 51.75 |
33.33 ± 57.74 |
25.00 ± 45.23 |
18.00 ± 38.81 |
0.0572 |
Feeding tube |
0.00 ± 0.00 |
0.00 ± 0.00 |
8.33 ± 28.87 |
0.00 ± 0.00 |
0.1655 |
Weight loss |
37.50 ± 51.75 |
33.33 ± 57.74 |
16.67 ± 38.92 |
22.00 ± 41.85 |
0.7149 |
Weight gain |
37.50 ± 51.75 |
0.00 ± 0.00 |
58.33 ± 51.49 |
52.00 ± 50.47 |
0.2820 |